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一名年轻女性移民中的腹部结核——非流行国家的“伟大伪装者”——病例报告及文献综述

Abdominal Tuberculosis in a Young Female Immigrant-"the Great Masquerader" in a Nonendemic Country-a Case Report and Literature Review.

作者信息

Dimova Ana, Fures Rajko, Konjevod Janja, Hrgovic Zlatko, Malojcic Sanja Malinac, Kranjcec Bojana

机构信息

Department of Surgery. Zabok General Hospital and Croatian Veterans Hospital, Zabok, Republic of Croatia.

Department of Gynecology and Obstetrics. Zabok General Hospital and Croatian Veterans Hospital, Zabok, Republic of Croatia.

出版信息

Mater Sociomed. 2025;37(2):169-174. doi: 10.5455/msm.2025.37.169-174.

DOI:10.5455/msm.2025.37.169-174
PMID:40607095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12212218/
Abstract

BACKGROUND

Tuberculosis (TB), primarily recognized as a pulmonary disease, can manifest in various extrapulmonary forms, with abdominal tuberculosis (ATB) being one of the most common. Abdominal tuberculosis is one of the diseases known as "the great imitator" - it can mimic the clinical presentation of various diseases that are more common, such as appendicitis, acute cholecystitis, colitis, and some malignant diseases such as colon or stomach neoplasms. Diagnosis of ATB is often delayed, especially if a clinician in a nonendemic country does not include ATB in the differential diagnosis. Given the rising migration of people from the endemic to the nonendemic countries, we believe it is mandatory to raise consciousness about this clinical entity, as well as to lower a threshold to include ATB in the differential diagnosis.

OBJECTIVE

We present a case of a 31-year-old patient from Nepal, who was admitted through the emergency department of General Hospital Zabok, Croatia, with signs of acute abdomen, later successfully diagnosed and treated for ATB.

CASE PRESENTATION

We also deliver a brief literature review, summarizing the epidemiology, clinical presentation, diagnostic and therapeutic algorithms for ATB. Migrations are inevitably changing the vaccination status and epidemiological risks of any host country.

CONCLUSION

Medical personnel should keep upgrading and revising their knowledge of the "usual suspects" whilst differentially diagnosing both immigrants and non-immigrants, in order to make timely and good quality diagnosis and treatment.

摘要

背景

结核病(TB)主要被认为是一种肺部疾病,但也可表现为多种肺外形式,腹部结核(ATB)是最常见的肺外结核之一。腹部结核是被称为“伟大模仿者”的疾病之一——它可以模仿各种更常见疾病的临床表现,如阑尾炎、急性胆囊炎、结肠炎,以及一些恶性疾病,如结肠或胃部肿瘤。ATB的诊断往往会延迟,特别是如果非结核病流行国家的临床医生在鉴别诊断中未将ATB考虑在内。鉴于从结核病流行国家向非流行国家迁移的人口不断增加,我们认为有必要提高对这一临床实体的认识,并降低在鉴别诊断中纳入ATB的门槛。

目的

我们报告一例来自尼泊尔的31岁患者,该患者通过克罗地亚扎博克总医院急诊科入院,有急腹症体征,后来被成功诊断为ATB并接受治疗。

病例介绍

我们还进行了简要的文献综述,总结了ATB的流行病学、临床表现、诊断和治疗算法。移民不可避免地会改变任何东道国的疫苗接种状况和流行病学风险。

结论

医务人员在对移民和非移民进行鉴别诊断时,应不断更新和复习对“常见嫌疑疾病”的认识,以便及时做出高质量的诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bbc/12212218/258d558104a1/MSM-37-169-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bbc/12212218/9839de688776/MSM-37-169-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bbc/12212218/258d558104a1/MSM-37-169-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bbc/12212218/9839de688776/MSM-37-169-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bbc/12212218/258d558104a1/MSM-37-169-g002.jpg

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本文引用的文献

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Systematic review of bovine and zoonotic tuberculosis in the Western Pacific and the Southeast Asia regions of the World Health Organization.世界卫生组织西太平洋和东南亚地区牛结核病和人畜共患结核病的系统评价。
Front Public Health. 2024 Jul 31;12:1345328. doi: 10.3389/fpubh.2024.1345328. eCollection 2024.
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New priorities for Croatia to pursue tuberculosis pre-elimination.克罗地亚实现结核病消除前期目标的新重点。
Eur Respir J. 2024 Jun 20;63(6). doi: 10.1183/13993003.00279-2024. Print 2024 Jun.
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Tuberculosis prevention: current strategies and future directions.
结核病预防:当前策略与未来方向。
Clin Microbiol Infect. 2024 Sep;30(9):1123-1130. doi: 10.1016/j.cmi.2023.10.023. Epub 2023 Oct 31.
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Abdominal Tuberculosis Mimicking Ovarian Malignancy.酷似卵巢恶性肿瘤的腹部结核
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Literature Highlights.文献亮点。
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Achieving universal access to rapid tuberculosis diagnostics.实现结核病快速诊断的普遍可及性。
BMJ Glob Health. 2023 May;8(5). doi: 10.1136/bmjgh-2023-012666.
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Abdominal visceral tuberculosis: a malignancy mimic.腹腔内脏结核:酷似恶性肿瘤。
Abdom Radiol (NY). 2023 Aug;48(8):2705-2715. doi: 10.1007/s00261-023-03939-5. Epub 2023 May 19.
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Evidence-based approach to diagnosis and management of abdominal tuberculosis.循证方法诊断和治疗腹部结核。
Indian J Gastroenterol. 2023 Feb;42(1):17-31. doi: 10.1007/s12664-023-01343-x. Epub 2023 Mar 11.
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