Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco 550 16th Street, 6th floor, UCSF Box 3213, San Francisco, CA 94158, USA.
Department of Hematology and Oncology, University of California San Francisco, 1825 4th Street, San Francisco, CA 94158, USA.
Otolaryngol Clin North Am. 2021 Jun;54(3):613-627. doi: 10.1016/j.otc.2021.01.007.
Despite aggressive initial interventions, recurrent/metastatic salivary gland cancer is not uncommon. Standard chemotherapy has not been shown to have durable clinical benefits. Several potential molecular markers have been identified in different histologic subtypes of salivary cancers. The objective of this review is to highlight the molecular markers that have been targeted in clinical trials for salivary gland cancers.
尽管进行了积极的初始干预，复发性/转移性唾液腺癌仍不少见。标准化疗并未显示出持久的临床获益。在不同组织学亚型的唾液腺癌中已经确定了几种潜在的分子标志物。本文旨在强调已在唾液腺癌临床试验中靶向的分子标志物。
