Shoushtar Faculty of Medical Sciences, Shoushtar, Iran.
Khatam Al-Anbia Hospital, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran.
Clin Nutr ESPEN. 2021 Jun;43:276-282. doi: 10.1016/j.clnesp.2021.03.040. Epub 2021 Apr 18.
COVID-19 is a global public health concern. As no standard treatment has been found for it yet, several minerals and vitamins with antioxidants, immunomodulators, and antimicrobials roles can be sufficient for the immune response against the disease. The present study evaluates the serum vitamin D, calcium, and Zinc levels in patients with COVID-19.
MATERIALS & METHODS: This research is a case-control study performed in May 2020 on 93 patients with COVID-19 hospitalized in a Shoushtar city hospital and on 186 healthy subjects with no symptoms of COVID-19. The serum vitamin D, calcium, and zinc levels were collected and analyzed using correlation coefficient and independent t-test via SPSS 18.
Vitamin D levels had a significant difference between the case and control groups (p = 0.008). Serum calcium and serum zinc levels also had statistically significant differences between the two groups (p < 0.001).
The research results showed that serum zinc, calcium, and vitamin D levels in COVID-19 patients are lower than in the control group. The supplementation with such nutrients is a safe and low-cost measure that can help cope with the increased demand for these nutrients in risk of acquiring the COVID-19 virus.
COVID-19 是一个全球性的公共卫生问题。由于目前尚未找到针对它的标准治疗方法，因此具有抗氧化、免疫调节和抗菌作用的一些矿物质和维生素可能足以应对这种疾病的免疫反应。本研究评估了 COVID-19 患者的血清维生素 D、钙和锌水平。
这是 2020 年 5 月在 Shoushtar 市医院对 93 名 COVID-19 住院患者和 186 名无 COVID-19 症状的健康受试者进行的病例对照研究。通过 SPSS 18 采用相关系数和独立 t 检验收集和分析血清维生素 D、钙和锌水平。
病例组和对照组之间维生素 D 水平有显著差异（p=0.008）。两组间血清钙和血清锌水平也有统计学差异（p<0.001）。
研究结果表明，COVID-19 患者的血清锌、钙和维生素 D 水平低于对照组。补充这些营养素是一种安全且低成本的措施，可以帮助满足感染 COVID-19 病毒风险增加对这些营养素的需求。
