Department of Gastroenterology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Clin Nutr ESPEN. 2021 Jun;43:377-382. doi: 10.1016/j.clnesp.2021.03.020. Epub 2021 Apr 1.
We conducted the present study to investigate the nutritional status of critically ill COVID-19 patients and validate the GLIM criteria with respect to the SGA.
In this prospective cohort study, 109 ICU patients were assessed for malnutrition based on GLIM and SGA criteria. The relation between nutrition assessment tools and duration of hospitalization and mortality were also evaluated. The sensitivity and specificity of GLIM criteria concerning the detection of malnutrition was assessed based on the area under the curve.
Malnutrition, according to the SGA and GLIM criteria, was found in 68 (62.4%) and 66 (61.5%) of our subjects. There was an optimal agreement between the GLIM criteria and the SGA criteria regarding malnutrition diagnosis (K = 0.85, P < 0.001). The area under curve for the GLIM was stratified based on the SGA results and was 0.927 (95% CI: 0.868-0.985) with a sensitivity and specificity of 92% and 93%, respectively.
Malnutrition is frequently observed in critically ill COVID-19 patients. GLIM criteria is a valid tool and has a strong association with mortality and longer duration of ICU stay.
本研究旨在调查 COVID-19 危重症患者的营养状况，并验证 GLIM 标准与 SGA 的相关性。
在这项前瞻性队列研究中，根据 GLIM 和 SGA 标准评估了 109 例 ICU 患者的营养不良情况。还评估了营养评估工具与住院时间和死亡率之间的关系。根据曲线下面积评估 GLIM 标准检测营养不良的敏感性和特异性。
根据 SGA 和 GLIM 标准，我们的研究对象中有 68（62.4%）和 66（61.5%）例存在营养不良。GLIM 标准与 SGA 标准在营养不良诊断方面具有最佳一致性（K=0.85，P<0.001）。GLIM 的曲线下面积根据 SGA 结果分层，为 0.927（95%CI：0.868-0.985），敏感性和特异性分别为 92%和 93%。
危重症 COVID-19 患者常存在营养不良。GLIM 标准是一种有效的工具，与死亡率和 ICU 住院时间延长有很强的关联。
