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Dual-resolution molecular dynamics simulation of antimicrobials in biomembranes.双分辨率分子动力学模拟生物膜中的抗菌剂。
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本文引用的文献

1
BACTERIOLOGICAL STUDIES RELATING TO HANDWASHING. 1. THE INABILITY OF SOAP BARS TO TRANSMIT BACTERIA.与洗手相关的细菌学研究。1. 肥皂块无法传播细菌。
Am J Public Health Nations Health. 1965 Jun;55(6):915-22. doi: 10.2105/ajph.55.6.915.
2
Nosocomial infections: washing away the problem.医院感染:洗去问题。
Med World News. 1983 Sep 26;24(18):41, 44-5, 49-52.
3
Microbial flora of in-use soap products.在用肥皂产品的微生物菌群。
Appl Environ Microbiol. 1984 Aug;48(2):338-41. doi: 10.1128/aem.48.2.338-341.1984.
4
Contamination of bar soaps under "in-use" conditions.“使用中”条件下巴皂的污染情况。
J Environ Pathol Toxicol Oncol. 1984 Jul;5(4-5):1-14.
5
Blood flow sensor developed; rate of flow of blood related to electrical conductivity.已开发出血流传感器;血流速率与电导率相关。
Hosp Manage. 1967 Feb;103(2):74-5.
6
A new method for the quantitative investigation of cutaneous bacteria.一种用于皮肤细菌定量研究的新方法。
J Invest Dermatol. 1965 Dec;45(6):498-503. doi: 10.1038/jid.1965.164.
7
Bar soap and liquid soap.香皂和液体皂。
JAMA. 1985 Mar 15;253(11):1560-1. doi: 10.1001/jama.1985.03350350054017.
8
Handwashing practices for the prevention of nosocomial infections.预防医院感染的洗手措施。
Ann Intern Med. 1975 Nov;83(5):683-90. doi: 10.7326/0003-4819-83-5-683.
9
Handwashing and antiseptic-containing soaps in hospital.医院中的洗手与含抗菌剂肥皂
J Clin Pathol. 1979 Jul;32(7):732-7. doi: 10.1136/jcp.32.7.732.

用受污染的块状肥皂洗手不太可能传播细菌。

Washing with contaminated bar soap is unlikely to transfer bacteria.

作者信息

Heinze J E, Yackovich F

机构信息

Dial Corporation, Dial Technical Center, Scottsdale, AZ 85254.

出版信息

Epidemiol Infect. 1988 Aug;101(1):135-42. doi: 10.1017/s0950268800029290.

DOI:10.1017/s0950268800029290
PMID:3402545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2249330/
Abstract

Recent reports of the isolation of microorganisms from used soap bars have raised the concern that bacteria may be transferred from contaminated soap bars during handwashing. Since only one study addressing this question has been published, we developed an additional procedure to test this concern. In our new method prewashed and softened commercial deodorant soap bars (0.8% triclocarban) not active against Gram-negative bacteria were inoculated with Escherichia coli and Pseudomonas aeruginosa to give mean total survival levels of 4.4 X 10(5) c.f.u. per bar which was 70-fold higher than those reported on used soap bars. Sixteen panelists were instructed to wash with the inoculated bars using their normal handwashing procedure. After washing, none of the 16 panelists had detectable levels of either test bacterium on their hands. Thus, the results obtained using our new method were in complete agreement with those obtained with the previously published method even though the two methods differ in a number of procedural aspects. These findings, along with other published reports, show that little hazard exists in routine handwashing with previously used soap bars and support the frequent use of soap and water for handwashing to prevent the spread of disease.

摘要

近期关于从用过的肥皂块中分离出微生物的报道引发了人们的担忧,即洗手过程中细菌可能会从受污染的肥皂块上转移。由于仅发表了一项针对该问题的研究,我们开发了一种额外的程序来检验这一担忧。在我们的新方法中,将预先洗涤并软化的市售除臭肥皂块(含0.8%三氯卡班,对革兰氏阴性菌无活性)接种大肠杆菌和铜绿假单胞菌,使每块肥皂的平均总存活菌数达到4.4×10⁵ c.f.u.,这比用过的肥皂块上报道的菌数高70倍。16名受试者按照其正常洗手程序用接种后的肥皂块洗手。洗手后,16名受试者手上均未检测到任何一种受试细菌。因此,尽管这两种方法在许多程序方面存在差异,但使用我们新方法获得的结果与先前发表的方法获得的结果完全一致。这些发现以及其他已发表的报告表明,使用用过的肥皂块进行常规洗手几乎不存在危害,并支持经常使用肥皂和水洗手以预防疾病传播。