McBride M E
Appl Environ Microbiol. 1984 Aug;48(2):338-41. doi: 10.1128/aem.48.2.338-341.1984.
A comparison has been made of the in-use bacterial load of two bar soaps with and without antibacterials and two liquid soaps in five different locations over a 1-week period. Of the 25 samples taken from each soap, 92 to 96% of samples from bar soaps were culture positive as compared to 8% of those from liquid soaps. Bacterial populations ranged from 0 to 3.8 log CFU per sample for bar soaps and from 0 to 2.0 log CFU per sample for liquid soaps. The mean bacterial populations per sample were 1.96 and 2.47 log CFU for the two bar soaps, and 0.08 and 0.12 log CFU for the two liquid soaps. The difference in bacterial population between bar soaps and liquid soaps was statistically significant (P = 0.005). Staphylococcus aureus was isolated on three occasions from bar soaps but not from liquid soaps. S. aureus was isolated twice from the exterior of the plastic dispensers of liquid soap but not from the soap itself. Gram-negative bacteria were cultured only from soaps containing antibacterials. Bacterial populations on bar soaps were not high compared with bacterial populations on hands, and the flora was continually changing without evidence of a carrier state.
在为期1周的时间里，对两种含抗菌剂和不含抗菌剂的条形肥皂以及两种液体肥皂在五个不同地点的使用中细菌载量进行了比较。从每种肥皂中采集的25个样本中，条形肥皂样本的92%至96%培养呈阳性，而液体肥皂样本的这一比例为8%。条形肥皂每个样本的细菌数量范围为0至3.8 log CFU，液体肥皂每个样本的细菌数量范围为0至2.0 log CFU。两种条形肥皂每个样本的平均细菌数量分别为1.96和2.47 log CFU，两种液体肥皂的平均细菌数量分别为0.08和0.12 log CFU。条形肥皂和液体肥皂之间的细菌数量差异具有统计学意义（P = 0.005）。金黄色葡萄球菌在条形肥皂中分离出3次，但在液体肥皂中未分离出。金黄色葡萄球菌在液体肥皂塑料分配器外部分离出2次，但未从肥皂本身分离出。革兰氏阴性菌仅从含抗菌剂的肥皂中培养出。与手上的细菌数量相比，条形肥皂上的细菌数量并不高，而且菌群不断变化，没有携带状态的证据。
