Hoffmann Arkadiusz, Kleniewska Paulina, Pawliczak Rafał
Department of Immunopathology, Faculty of Biomedical Sciences and Postgraduate Training, Medical University of Lodz, Lodz, Poland.
Arch Med Sci. 2019 Nov 21;17(3):792-804. doi: 10.5114/aoms.2019.89894. eCollection 2021.
Probiotics are defined as live microorganisms that have a beneficial effect on health by exhibiting quantitative and qualitative effects on intestinal microflora and/or modification of the immune system. A strain is considered probiotic if it demonstrates a series of clinically proven health benefits. In recent years, the number of studies related to the antioxidant properties of probiotics has significantly increased. Antioxidants are substances that inhibit the degree of oxidation of molecules and cause the transformation of radicals into inactive derivatives. The incorrect or inefficient antioxidant mechanisms results in oxidative stress and may occur in the course of many diseases such as diabetes, atherosclerosis, inflammatory bowel disease or damage to the heart, brain or transplanted organs. Correct functioning of antioxidant mechanisms seems to be crucial for the proper functioning of our body; therefore, probiotics should be carefully investigated for potential antioxidant properties.
益生菌被定义为一类活的微生物，它们通过对肠道微生物群产生定量和定性影响及/或改变免疫系统而对健康产生有益作用。如果一种菌株表现出一系列经临床证实的健康益处，那么它就被认为是益生菌。近年来，与益生菌抗氧化特性相关的研究数量显著增加。抗氧化剂是抑制分子氧化程度并使自由基转化为无活性衍生物的物质。不正确或低效的抗氧化机制会导致氧化应激，并且可能发生在许多疾病过程中，如糖尿病、动脉粥样硬化、炎症性肠病或心脏、大脑或移植器官的损伤。抗氧化机制的正常运作似乎对我们身体的正常功能至关重要；因此，应仔细研究益生菌的潜在抗氧化特性。
