一项关于肌肉注射氯胺酮治疗严重且持久的饮食失调症合并难治性抑郁症患者的纵向病例系列研究。
A longitudinal case series of IM ketamine for patients with severe and enduring eating disorders and comorbid treatment-resistant depression.
作者信息
Schwartz Terry, Trunko Mary Ellen, Feifel David, Lopez Emily, Peterson Danika, Frank Guido K W, Kaye Walter
机构信息
Department of Psychiatry University of California San Diego San Diego CA USA.
出版信息
Clin Case Rep. 2021 Apr 4;9(5):e03869. doi: 10.1002/ccr3.3869. eCollection 2021 May.
Severe and enduring eating disorders (EDs) have the highest mortality rate of all psychiatric illnesses (Arch Gen Psychiatry, 2011, , 724), especially when comorbid with treatment-resistant depression (TRD) (Psychiatr Res, 2016, , 45). We report on four patients with enduring EDs and TRD treated with repeat ketamine over 12 + months, showing improvement in depression with only modest changes in ED symptoms.
严重且持久的饮食失调症（EDs）在所有精神疾病中死亡率最高（《美国精神病学杂志》，2011年，第724页），尤其是与难治性抑郁症（TRD）共病时（《精神病学研究》，2016年，第45页）。我们报告了4例患有持久EDs和TRD的患者，他们在12个多月的时间里接受了重复氯胺酮治疗，结果显示抑郁症症状有所改善，而ED症状仅有适度变化。
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