School of Public Health, Fudan University, Shanghai, China.
College of Pharmacy, Jinan University, Guangzhou, China.
Eur J Health Econ. 2021 Sep;22(7):1083-1093. doi: 10.1007/s10198-021-01307-y. Epub 2021 Apr 24.
To assess measurement properties of the two youth versions of EQ-5D (i.e., 5-level EQ-5D-Y [Y-5L] and 3-level EQ-5D-Y [Y-3L]) and KIDSCREEN-10 in China.
Children and adolescents attending schools in Shanghai, China were recruited to self-complete the Y-5L, KIDSCREEN-10, and Y-3L questionnaires. Their feasibility was assessed according to missing responses. Convergent validity of the EQ-5D-Y dimensions, a summated dimension score [SDS], and Visual Analogue Scale (VAS) were assessed by examining their correlations with the KIDSCREEN-10 index score and dimensions. Known-groups validity of SDS, VAS, and KIDSCREEN-10 index score were tested by comparing the scores of pupils with and without two conditions (i.e., overweight and shortsightedness), and the relative efficiency (RE) between them was also evaluated.
A total of 262 pupils (girl: 58.4%; mean age: 12.7 years) were enrolled. Missing responses were low for both the Y-5L (0.3%) and Y-3L (2.4%), and KIDSCREEN-10 (0.3%). The overall ceiling effects were 40.3% for the Y-5L, 44.1% for the Y-3L and 1.1% for the KIDSCREEN-10. The SDS, SDS and VAS were moderately correlated with the KIDSCREEN-10 index score (|r|= 0.425 for SDS, 0.323 for SDS, and 0.435 for VAS; p < 0.01 for all). Similar EQ-5D-Y and KIDSCREEN-10 dimensions showed moderate to strong correlations (|r|> 0.3). Both the SDS and SDS had lower values, and VAS and KIDSCREEN-10 index score had higher values for pupils without shortsightedness compared with those for their counterparts. The difference was statistical significance for the SDS and VAS (P < 0.05 for both), which also had higher RE in the condition.
The Y-5L, Y-3L, and KIDSCREEN-10 questionnaires are feasible and valid for measuring HRQoL among children/adolescents in China. It also appears that the advantages of Y-5L over Y-3L were modest.
评估 EQ-5D 的两个青年版本(即 5 级 EQ-5D-Y [Y-5L]和 3 级 EQ-5D-Y [Y-3L])和 KIDSCREEN-10 在我国的测量特性。
在中国上海的学校就读的儿童和青少年被招募来自我完成 Y-5L、KIDSCREEN-10 和 Y-3L 问卷。根据缺失的反应评估它们的可行性。通过检查与 KIDSCREEN-10 指数得分和维度的相关性,评估 EQ-5D-Y 维度、总和维度得分 [SDS]和视觉模拟量表(VAS)的收敛效度。通过比较有和没有两种情况(即超重和近视)的小学生的 SDS、VAS 和 KIDSCREEN-10 指数得分来测试 SDS、VAS 和 KIDSCREEN-10 指数得分的已知组有效性,并评估它们之间的相对效率(RE)。
共纳入 262 名小学生(女生:58.4%;平均年龄:12.7 岁)。Y-5L(0.3%)和 Y-3L(2.4%)以及 KIDSCREEN-10(0.3%)的缺失反应率均较低。Y-5L 的总上限效应为 40.3%,Y-3L 为 44.1%,KIDSCREEN-10 为 1.1%。SDS、SDS 和 VAS 与 KIDSCREEN-10 指数得分中度相关(SDS 的 |r|=0.425,SDS 的 |r|=0.323,VAS 的 |r|=0.435;p<0.01 均)。相似的 EQ-5D-Y 和 KIDSCREEN-10 维度显示出中度至强的相关性(|r|>0.3)。与近视的小学生相比,无近视的小学生的 SDS 和 SDS 得分较低,VAS 和 KIDSCREEN-10 指数得分较高。SDS 和 VAS 的差异具有统计学意义(p<0.05 均),并且在该条件下具有更高的 RE。
Y-5L、Y-3L 和 KIDSCREEN-10 问卷在测量中国儿童/青少年的 HRQoL 方面是可行和有效的。Y-5L 优于 Y-3L 的优势似乎也不大。