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德国最年长人群(85 岁及以上)的 EQ-5D-3L 健康状况和健康状态效用:AgeCoDe-AgeQualiDe 研究结果。

EQ-5D-3L health status and health state utilities of the oldest-old (85 +) in Germany: results from the AgeCoDe-AgeQualiDe study.

机构信息

Department of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

出版信息

Qual Life Res. 2020 Dec;29(12):3223-3232. doi: 10.1007/s11136-020-02597-0. Epub 2020 Aug 26.

Abstract

PURPOSE

To describe health status and health state utilities measured by the EQ-5D-3L in a population-based sample of individuals aged 85 + in Germany, and to analyze associations with basic socio-demographic variables.

METHODS

Cross-sectional data from follow-up wave 7 (n = 761) of the German AgeCoDe Study were used. The EQ-5D-3L questionnaire was used to record problems in five health dimensions, its visual analogue scale (EQ VAS) was used to record self-rated health status, and the German EQ-5D-3L index was used to derive health state utilities.

RESULTS

Mean age of respondents was 88.9 years (SD 2.9; range 85 to 100), 67.4% were female. 81.9% reported problems in at least one of the EQ-5D dimensions, with 15.3% reporting extreme problems. Most frequent were problems with pain/discomfort (64.8%), followed by mobility (62.5%), usual activities (42.6%), self-care (28.2%), and anxiety/depression (20.5%). Mean EQ VAS score was 62.4 (SD 18.8), and mean EQ-5D index was 0.77 (SD 0.24). Multiple regression analysis showed associations of problem frequency in various EQ-5D dimensions with age, gender, living situation, marital status, and education. The EQ VAS score was negatively associated with age (β =  - 0.56; p < 0.05) and female gender (β =  - 3.49; p < 0.05). The EQ-5D index was negatively associated with not living in the community (β =  - 0.10; p < 0.001) and being single (β =  - 0.09; p < 0.05).

CONCLUSIONS

The results show a substantially impaired health status of the oldest-old population. The data can be used for comparing health status of population groups as well as for health economic models.

摘要

目的

描述德国基于人群的 85 岁以上个体样本中使用 EQ-5D-3L 测量的健康状况和健康状态效用,并分析与基本社会人口统计学变量的关联。

方法

使用德国 AgeCoDe 研究的随访第 7 波(n=761)的横断面数据。使用 EQ-5D-3L 问卷记录五个健康维度的问题,使用 EQ VAS 记录自我报告的健康状况,使用德国 EQ-5D-3L 指数得出健康状态效用。

结果

受访者的平均年龄为 88.9 岁(SD 2.9;范围 85 至 100),67.4%为女性。81.9%的人报告至少有一个 EQ-5D 维度存在问题,15.3%的人报告存在极端问题。最常见的问题是疼痛/不适(64.8%),其次是行动不便(62.5%)、日常活动(42.6%)、自我护理(28.2%)和焦虑/抑郁(20.5%)。平均 EQ VAS 评分为 62.4(SD 18.8),平均 EQ-5D 指数为 0.77(SD 0.24)。多元回归分析显示,各种 EQ-5D 维度的问题发生率与年龄、性别、居住状况、婚姻状况和教育程度有关。EQ VAS 评分与年龄呈负相关(β=-0.56;p<0.05),与女性性别呈负相关(β=-3.49;p<0.05)。EQ-5D 指数与不住在社区(β=-0.10;p<0.001)和单身(β=-0.09;p<0.05)呈负相关。

结论

结果表明,最年长人群的健康状况明显受损。这些数据可用于比较人群群体的健康状况,也可用于健康经济模型。

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