Julian Katherine, Bucher Donald, Jain Rohit
Penn State College of Medicine, Hershey, Pennsylvania, USA
Department of Internal Medicine, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA.
BMJ Case Rep. 2021 May 24;14(5):e243315. doi: 10.1136/bcr-2021-243315.
We describe the case of a 65-year-old male who presented to an outside hospital for shortness of breath, nausea and vomiting 8 days after testing positive for COVID-19. Initial workup revealed massive bilateral pulmonary emboli and thrombocytopenia. The patient was then admitted to our hospital, received an inferior vena cava filter and initially started on argatroban for autoimmune heparin-induced thrombocytopenia (HIT) prophylaxis. On hospital stay day 6, labs revealed a diagnosis of HIT in the setting of COVID-19. This case highlights the rare occurrence of a patient developing HIT without heparin exposure and in the setting of a novel infectious agent, COVID-19.
我们描述了一名65岁男性的病例，该患者在新冠病毒检测呈阳性8天后因呼吸急促、恶心和呕吐前往外院就诊。初步检查发现双侧大面积肺栓塞和血小板减少症。随后患者被收治入我院，植入了下腔静脉滤器，并开始使用阿加曲班以预防自身免疫性肝素诱导的血小板减少症（HIT）。住院第6天，实验室检查确诊该患者在新冠病毒感染背景下发生了HIT。该病例凸显了在未接触肝素且在新型感染因子新冠病毒感染背景下发生HIT的罕见情况。
