Semenciw R M, Morrison H I, Mao Y, Johansen H, Davies J W, Wigle D T
Bureau of Non-Communicable Disease Epidemiology, Department of National Health and Welfare, Ottawa, Canada.
Int J Epidemiol. 1988 Jun;17(2):317-24. doi: 10.1093/ije/17.2.317.
The cardiovascular mortality experience of over 7000 Canadians ages 35-79 years free of self-reported heart disease or stroke who participated in the Nutrition Canada survey is presented. The effects of various risk factors on cardiovascular disease mortality were assessed using multivariate Poisson regression analyses. Factors associated with a significantly increased risk of dying included cigarette smoking, hypertension, diabetes and, for women, serum cholesterol. Relative risks were similar for those ages 35-64 years compared to those 65-79 years for diabetes but were higher among those 35-64 years for cigarette smoking, diastolic hypertension, obesity and serum cholesterol (females only). Individuals drinking three or more drinks daily had a relative risk of 3.18 for stroke. Population attributable risks for smoking, hypertension, elevated serum cholesterol and diabetes, respectively, were 47%, 21%, 7% and 8% for men and 10%, 21% 18% and 16% for women.
本文呈现了7000多名年龄在35 - 79岁、自我报告无心脏病或中风的加拿大参与者在加拿大营养调查中的心血管疾病死亡情况。使用多变量泊松回归分析评估了各种风险因素对心血管疾病死亡率的影响。与死亡风险显著增加相关的因素包括吸烟、高血压、糖尿病，对女性而言还包括血清胆固醇。35 - 64岁人群与65 - 79岁人群相比，糖尿病的相对风险相似，但在35 - 64岁人群中，吸烟、舒张压高血压、肥胖和血清胆固醇（仅女性）的相对风险更高。每天饮用三杯或更多酒的个体中风的相对风险为3.18。男性吸烟、高血压、血清胆固醇升高和糖尿病的人群归因风险分别为47%、21%、7%和8%，女性分别为10%、21%、18%和16%。
