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心血管疾病危险因素持续下降:明尼苏达心脏调查结果,1980 - 1982年和1985 - 1987年

Continued decline in cardiovascular disease risk factors: results of the Minnesota Heart Survey, 1980-1982 and 1985-1987.

作者信息

Sprafka J M, Burke G L, Folsom A R, Luepker R V, Blackburn H

机构信息

Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55455.

出版信息

Am J Epidemiol. 1990 Sep;132(3):489-500. doi: 10.1093/oxfordjournals.aje.a115685.

Abstract

Systematic, simultaneous surveillance of cardiovascular disease risk factors, morbidity, and mortality is ongoing in the Minnesota Heart Survey. Risk factors for cardiovascular disease were measured in population-based surveys of Twin Cities metropolitan area residents aged 25-74 years in 1980-1982 and 1985-1987. During this period, age-adjusted, average systolic blood pressure declined nonsignificantly in men and significantly in women, and average, age-adjusted diastolic blood pressure declined 1.1 mmHg in men and 0.9 mmHg in women. Between 1980-1982 and 1985-1987, serum total cholesterol declined significantly, 5.2 and 5.8 mg/dl in men and women, respectively. Serum high density lipoprotein cholesterol decreased 1.6 mg/dl in men and 0.9 mg/dl in women. The prevalence of cigarette smoking declined by 14% in men and 18% in women. In contrast, the average body mass index increased 0.6 kg/m2 in men and 1.2 kg/m2 in women. Systematic hospital and death certificate surveillance found that mortality rates for coronary heart disease in the Twin Cities metropolitan area declined 20.1% in men and 12.9% in women from 1981 to 1986. Despite difficulties in interpretation of ecologic studies, it appears likely that improvements in population risk factor levels played a role in the decline in disease rates and could influence future mortality trends in this population.

摘要

明尼苏达心脏调查正在对心血管疾病风险因素、发病率和死亡率进行系统、同步的监测。在1980 - 1982年以及1985 - 1987年针对明尼阿波利斯双城都会区25 - 74岁居民开展的基于人群的调查中,对心血管疾病风险因素进行了测量。在此期间,年龄调整后的平均收缩压在男性中下降不显著,在女性中显著下降;年龄调整后的平均舒张压在男性中下降了1.1 mmHg,在女性中下降了0.9 mmHg。在1980 - 1982年至1985 - 1987年期间,血清总胆固醇显著下降,男性和女性分别下降了5.2和5.8 mg/dl。血清高密度脂蛋白胆固醇在男性中下降了1.6 mg/dl,在女性中下降了0.9 mg/dl。男性吸烟率下降了14%,女性下降了18%。相比之下,男性的平均体重指数增加了0.6 kg/m²,女性增加了1.2 kg/m²。系统的医院和死亡证明监测发现,从1981年到1986年,双城都会区男性冠心病死亡率下降了20.1%,女性下降了12.9%。尽管生态学研究的解读存在困难,但人群风险因素水平的改善似乎在疾病率下降中发挥了作用,并可能影响该人群未来的死亡率趋势。

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