Elad D, Kamm R D, Shapiro A H
Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge 02139.
J Appl Physiol (1985). 1988 Jul;65(1):7-13. doi: 10.1152/jappl.1988.65.1.7.
A semiempirical model of a pressure-area relationship for the bronchial airways is developed. It is described by a single similarity law consistent in form with the nonlinear elastic behavior of biological tissue. The tethering effect of the parenchyma is lumped into the wall properties of the bronchi and is included in an effective wall stiffness. The model, which is fitted to the experimental data of Takishima and his associates (J. Appl. Physiol. 38: 875-881, 1975), is lung-volume dependent and is therefore suitable for the analyses of airflow at different lung volumes, especially for modeling of forced expiration.
建立了支气管气道压力-面积关系的半经验模型。它由一个单一的相似定律描述，其形式与生物组织的非线性弹性行为一致。实质组织的束缚效应被集中到支气管的壁特性中，并包含在有效壁刚度中。该模型与Takishima及其同事的实验数据（《应用生理学杂志》38:875 - 881,1975）拟合，它依赖于肺容积，因此适用于分析不同肺容积下的气流，特别是用于强制呼气的建模。
