Di Fabio José Luis, Cortés Castillo María de Los Ángeles, Griffiths Elwyn
Independent consultant Washington D.C United States of America Independent consultant, Washington D.C., United States of America.
Independent consultant Mexico City Mexico https://orcid.org/0000-0003-0029-665x Independent consultant, Mexico City, Mexico, https://orcid.org/0000-0003-0029-665x.
Rev Panam Salud Publica. 2021 May 20;45:e55. doi: 10.26633/RPSP.2021.55. eCollection 2021.
To assess the productivity and visibility in research, clinical studies, treatment, use and production of antivenoms against poisonous snakes, scorpions and spiders.
Bibliometric analysis of research and other activities. Articles on venoms and antivenoms published between 2000 and 2020 were retrieved from the Scopus database. The records were analyzed by bibliometric indicators including number of documents per year, journals, authors, and citation frequency. VOSviewer v.1.6.13 was used to construct bibliometric networks for country co-authorships and co-occurrence of terms.
Australia, Brazil, Costa Rica and India were among the six top countries with most documents and were selected for more detailed analysis. Costa Rica was the country with the largest percentage of its publications dedicated to antivenom production and venomics. Only a few papers dealt with the issues of quality, safety, and efficacy of antivenoms or the role of the national regulatory authorities. The use of VOSviewe allowed visualization through joint publications of networking between countries. Visualization by co-occurrence of terms showed differences in the research carried out.
Working in a collaborative and coordinated manner these four countries could have a major impact on envenoming globally. Attention should be given not only to antivenom production but also to strengthening regulatory oversight of antivenom products.
评估针对毒蛇、蝎子和蜘蛛的抗蛇毒血清在研究、临床研究、治疗、使用及生产方面的产出率和影响力。
对研究及其他活动进行文献计量分析。从Scopus数据库中检索2000年至2020年间发表的关于毒液和抗蛇毒血清的文章。通过文献计量指标对记录进行分析，包括每年的文献数量、期刊、作者及被引频次。使用VOSviewer v.1.6.13构建国家合著和术语共现的文献计量网络。
澳大利亚、巴西、哥斯达黎加和印度是文献数量最多的六个国家之一，并被选作更详细的分析对象。哥斯达黎加是其出版物中专门涉及抗蛇毒血清生产和毒液组学比例最高的国家。仅有少数论文涉及抗蛇毒血清的质量、安全性和有效性问题或国家监管当局的作用。使用VOSviewer能够通过各国之间的联合出版物实现网络可视化。术语共现的可视化展示了所开展研究的差异。
这四个国家若以协作和协调的方式开展工作，可能会对全球的蛇咬伤治疗产生重大影响。不仅应关注抗蛇毒血清的生产，还应加强对抗蛇毒血清产品的监管监督。
