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Tumor-Infiltrating Leukocyte Phenotypes Distinguish Outcomes in Related Patients With Pancreatic Adenocarcinoma.

作者信息

Link Jason M, Liudahl Shannon M, Betts Courtney B, Sivagnanam Shamilene, Leis Kenna R, McDonnell Mary, Pelz Carl R, Johnson Brett, Hamman Kelly J, Keith Dove, Sampson Jone E, Morgan Terry K, Lopez Charles D, Coussens Lisa M, Sears Rosalie C

机构信息

Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR.

Brenden-Colson Center for Pancreatic Care, Oregon Health and Science University, Portland, OR.

出版信息

JCO Precis Oncol. 2021 Feb 5;5. doi: 10.1200/PO.20.00287. eCollection 2021.

DOI:10.1200/PO.20.00287
PMID:34036232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8140804/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/086824c5bc4a/po-5-po.20.00287-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/dcb4dcca7c61/po-5-po.20.00287-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/82b5704f8a25/po-5-po.20.00287-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/7a990cd1453b/po-5-po.20.00287-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/3e4ab254b18f/po-5-po.20.00287-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/7d97677c7dc4/po-5-po.20.00287-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/086824c5bc4a/po-5-po.20.00287-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/dcb4dcca7c61/po-5-po.20.00287-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/82b5704f8a25/po-5-po.20.00287-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/7a990cd1453b/po-5-po.20.00287-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/3e4ab254b18f/po-5-po.20.00287-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/7d97677c7dc4/po-5-po.20.00287-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930c/8140804/086824c5bc4a/po-5-po.20.00287-g007.jpg

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Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation.胰腺癌细胞的鳞状转化促进了基质炎症。
Elife. 2020 Apr 24;9:e53381. doi: 10.7554/eLife.53381.
3
Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution.
胰腺癌的转录表型是由肿瘤进化过程中的基因组事件驱动的。
Nat Genet. 2020 Feb;52(2):231-240. doi: 10.1038/s41588-019-0566-9. Epub 2020 Jan 13.
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Purity Independent Subtyping of Tumors (PurIST), A Clinically Robust, Single-sample Classifier for Tumor Subtyping in Pancreatic Cancer.肿瘤纯度独立分型(PurIST):一种用于胰腺癌肿瘤分型的临床稳健的单样本分类器。
Clin Cancer Res. 2020 Jan 1;26(1):82-92. doi: 10.1158/1078-0432.CCR-19-1467. Epub 2019 Nov 21.
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