Krull F, Schuchardt V, Haupt W F, Mewes J
Neuropsychiatric University Clinic, Köln, FRG.
Intensive Care Med. 1988;14(4):388-92. doi: 10.1007/BF00262894.
We compared two selected groups of patients with acute Guillain-Barré syndrome requiring artificial ventilation. Both groups were treated with conventional therapy, group A (n = 35) between 1970 and 1978, group B (n = 21) between 1979 and 1983. Neither plasmapheresis nor any other immunosuppressive treatment was applied. Significant differences were found favouring group B: There was a decline of mortality from about 60% to less than 10% (p less than 0.001) and a smaller number of severe complications due to improvement of supportive care.
我们比较了两组因急性格林-巴利综合征需要人工通气的选定患者。两组均接受常规治疗，A组（n = 35）在1970年至1978年期间接受治疗，B组（n = 21）在1979年至1983年期间接受治疗。两组均未进行血浆置换或任何其他免疫抑制治疗。结果发现B组有显著优势：死亡率从约60%降至不到10%（p < 0.001），且由于支持治疗的改善，严重并发症的数量也更少。
