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吉兰-巴雷综合征的诊断考量

Diagnostic considerations in Guillain-Barré syndrome.

作者信息

Asbury A K

出版信息

Ann Neurol. 1981;9 Suppl:1-5. doi: 10.1002/ana.410090703.

DOI:10.1002/ana.410090703
PMID:7224610
Abstract

Guillain-Barré syndrome (GBS) is a recognized entity for which the basis for diagnosis is descriptive in our present state of knowledge. Diagnosis rests upon pattern recognition of the clinical picture plus other features including elevated cerebrospinal fluid protein level, electrophysiological changes of marked slowing of conduction velocities, prolonged distal latencies, dispersion of the evoked responses, and frequent evidence of conduction block, together with pathological changes, when known, of low grade-inflammation and demyelination-remyelination in peripheral nerve. The precise diagnostic limits of GBS remain uncertain.

摘要

吉兰-巴雷综合征(GBS)是一种已被认可的疾病,就我们目前的知识水平而言,其诊断依据是描述性的。诊断依赖于对临床表现的模式识别以及其他特征,包括脑脊液蛋白水平升高、传导速度明显减慢的电生理变化、远端潜伏期延长、诱发电位离散以及频繁出现的传导阻滞证据,还有已知的外周神经低度炎症和脱髓鞘-再髓鞘化的病理变化。GBS的确切诊断界限仍不明确。

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