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F-18氟脱氧葡萄糖正电子发射断层扫描在髓鞘少突胶质细胞糖蛋白抗体阳性自身免疫性癫痫中的代谢表型

F-18 Fluorodeoxyglucose Positron Emission Tomography Metabolic Phenotype in Myelin Oligodendrocyte Glycoprotein Antibody-Positive Autoimmune Epilepsy.

作者信息

Tripathi Madhavi, Sreedharan Thankarajan Arun Raj, Tripathi Manjari, Garg Ajay, Ramanujam Bhargavi, Bal Chandrasekhar

机构信息

Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

Department of Neurology, Cardiothoracic and Neurosciences Centre, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Nucl Med. 2021 Jan-Mar;36(1):88-89. doi: 10.4103/ijnm.IJNM_167_20. Epub 2021 Mar 4.

DOI:10.4103/ijnm.IJNM_167_20
PMID:34040310
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8130699/
Abstract

We describe the metabolic phenotype on F-18 fluorodeoxyglucose positron emission tomography (PET) in a 13-year-old female with myelin oligodendrocyte glycoprotein (MOG) antibody-positive encephalitis. Unilateral hemispheric hypometabolism on PET may be the metabolic phenotype of autoimmune epilepsy associated with MOG antibody.

摘要

我们描述了一名13岁患有髓鞘少突胶质细胞糖蛋白（MOG）抗体阳性脑炎的女性患者的F-18氟脱氧葡萄糖正电子发射断层扫描（PET）代谢表型。PET上的单侧半球代谢减低可能是与MOG抗体相关的自身免疫性癫痫的代谢表型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eba/8130699/bdf7052fa422/IJNM-36-88-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eba/8130699/bdf7052fa422/IJNM-36-88-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eba/8130699/bdf7052fa422/IJNM-36-88-g001.jpg

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本文引用的文献

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Myelin oligodendrocyte glycoprotein antibodies in neurological disease.髓鞘少突胶质细胞糖蛋白抗体与神经系统疾病
Nat Rev Neurol. 2019 Feb;15(2):89-102. doi: 10.1038/s41582-018-0112-x.
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Metabolic topography of autoimmune non-paraneoplastic encephalitis.自身免疫性非副肿瘤性脑炎的代谢地形图
Neuroradiology. 2018 Feb;60(2):189-198. doi: 10.1007/s00234-017-1956-2. Epub 2017 Dec 18.
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Abnormal brain metabolism on FDG-PET/CT is a common early finding in autoimmune encephalitis.氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG-PET/CT）显示的脑代谢异常是自身免疫性脑炎常见的早期表现。
Neurol Neuroimmunol Neuroinflamm. 2017 May 11;4(4):e352. doi: 10.1212/NXI.0000000000000352. eCollection 2017 Jul.
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Diagnostic Value of F-FDG PET/CT Versus MRI in the Setting of Antibody-Specific Autoimmune Encephalitis.F-FDG PET/CT与MRI在抗体特异性自身免疫性脑炎诊断中的价值比较
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MOG antibody-positive, benign, unilateral, cerebral cortical encephalitis with epilepsy.伴有癫痫发作的髓鞘少突胶质细胞糖蛋白（MOG）抗体阳性、良性、单侧大脑皮质脑炎
Neurol Neuroimmunol Neuroinflamm. 2017 Jan 16;4(2):e322. doi: 10.1212/NXI.0000000000000322. eCollection 2017 Mar.
6
[(18)F]-Fluoro-Deoxy-Glucose Positron Emission Tomography Scan Should Be Obtained Early in Cases of Autoimmune Encephalitis.自身免疫性脑炎病例应尽早进行[（18）F]-氟脱氧葡萄糖正电子发射断层扫描。
Autoimmune Dis. 2016;2016:9450452. doi: 10.1155/2016/9450452. Epub 2016 Jul 31.
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Antibodies to MOG in adults with inflammatory demyelinating disease of the CNS.抗髓鞘少突胶质细胞糖蛋白抗体在中枢神经系统炎症性脱髓鞘疾病中的作用。
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8
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