急性高血糖是否会影响热痛阈值？

Does acute hyperglycaemia influence heat pain thresholds?

作者信息

Chan A W, MacFarlane I A, Bowsher D R, Wells J C

机构信息

Diabetic Clinic, Walton Hospital, Liverpool, UK.

出版信息

J Neurol Neurosurg Psychiatry. 1988 May;51(5):688-90. doi: 10.1136/jnnp.51.5.688.

DOI:10.1136/jnnp.51.5.688

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1033078/

Abstract

The influence of acute hyperglycaemia on pain sensation was assessed in eight young adult non-diabetic subjects. Acute hyperglycaemia was induced with IV glucose in a double blind fashion, with IV saline as a control. Pain thresholds were assessed by a painful heat stimulus delivered by a Marstock thermode on the thenar eminence. Heat pain thresholds did not significantly alter during either acute hyperglycaemia or the control saline infusion. Previous work demonstrating a lowering of electrical pain thresholds by hyperglycaemia has therefore not been confirmed using a natural painful stimulus.

摘要

在八名年轻的非糖尿病成年受试者中评估了急性高血糖对痛觉的影响。以双盲方式通过静脉注射葡萄糖诱导急性高血糖，以静脉注射生理盐水作为对照。通过Marstock热刺激器在鱼际隆起处施加疼痛性热刺激来评估疼痛阈值。在急性高血糖或对照生理盐水输注期间，热痛阈值均未发生显著变化。因此，先前关于高血糖会降低电痛阈值的研究结果，在使用自然疼痛刺激时并未得到证实。

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