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2021 年德国对儿童保育中心疫情的调查推断出 SARS-CoV-2 变异株 B.1.1.7 儿童和成人的易感性和传染性。

SARS-CoV-2 variant B.1.1.7 susceptibility and infectiousness of children and adults deduced from investigations of childcare centre outbreaks, Germany, 2021.

机构信息

Department for Infectious Disease Epidemiology, Robert Koch-Institute, Berlin, Germany.

These authors contributed equally to this article and share first authorship.

出版信息

Euro Surveill. 2021 May;26(21). doi: 10.2807/1560-7917.ES.2021.26.21.2100433.

DOI:10.2807/1560-7917.ES.2021.26.21.2100433
PMID:34047274
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8161729/
Abstract

We investigated three SARS-CoV-2 variant B.1.1.7 childcare centre and related household outbreaks. Despite group cohorting, cases occurred in almost all groups, i.e. also among persons without close contact. Children's secondary attack rates (SAR) were similar to adults (childcare centres: 23% vs 30%; p = 0.15; households: 32% vs 39%; p = 0.27); child- and adult-induced household outbreaks also led to similar SAR. With the advent of B.1.1.7, susceptibility and infectiousness of children and adults seem to converge. Public health measures should be revisited accordingly.

摘要

我们调查了三起与 SARS-CoV-2 变异株 B.1.1.7 相关的儿童保育中心和家庭暴发疫情。尽管进行了群体分组,但几乎所有群体都出现了病例,即使是那些没有密切接触的人。儿童的二次攻击率(SAR)与成年人相似(儿童保育中心:23%比 30%;p=0.15;家庭:32%比 39%;p=0.27);儿童和成人引发的家庭暴发疫情也导致了相似的 SAR。随着 B.1.1.7 的出现,儿童和成人的易感性和传染性似乎趋同。公共卫生措施应相应进行调整。

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