Department of Epidemiology, The University of Florida, United States.
Department of Epidemiology, Florida International University, United States.
Drug Alcohol Depend. 2021 Aug 1;225:108770. doi: 10.1016/j.drugalcdep.2021.108770. Epub 2021 May 21.
Emerging literature shows increased drug use during the COVID-19 pandemic. However, limited research has examined the change in marijuana use among persons living with HIV (PLWH). This study aimed to investigate how marijuana use changed in a cohort of PLWH during the first year of the pandemic and identify factors associated with the change.
222 PLWH (mean age = 50.2 ± 11.2, 50.9 % female, 14.5 % Hispanic, 64.7 % Black, 15.8 % White, 5 % other, 80.2 % persons using marijuana [at least weekly use], 19.8 % persons not using marijuana) completed a baseline survey on demographics and behavioral/health characteristics between 2018 and 2020 and a brief phone survey between May and October 2020 that assessed changes in marijuana use and overall/mental health, and perceived risks/benefits of marijuana use during the COVID-19 pandemic.
During the pandemic, 64/222(28.8 %) of the whole sample reported increased marijuana use, 36(16.2 %) reported decreased use, and 122(55 %) reported no change. Multinomial logistic regression results indicated that: Compared to those reporting no change, increased marijuana use during the pandemic was associated with more frequent marijuana use and PTSD symptoms at baseline, worsened mental health during the pandemic, and not perceiving marijuana use as a risk factor for COVID-19 infection. More frequent marijuana use at baseline was the only factor significantly associated with decreased marijuana use during the pandemic.
The COVID-19 pandemic has resulted in changes in marijuana use among a considerable proportion (45 %) of PLWH. Future research is needed to understand the temporality of the increases in marijuana use with worsening mental health.
新出现的文献表明，在 COVID-19 大流行期间药物使用有所增加。然而，有限的研究调查了艾滋病毒感染者（PLWH）中大麻使用的变化。本研究旨在调查在大流行的第一年，PLWH 群体中大麻使用情况的变化，并确定与变化相关的因素。
222 名 PLWH（平均年龄=50.2±11.2，50.9%为女性，14.5%为西班牙裔，64.7%为黑人，15.8%为白人，5%为其他，80.2%的人为大麻使用者（至少每周使用一次），19.8%的人不使用大麻）在 2018 年至 2020 年之间完成了一项关于人口统计学和行为/健康特征的基线调查，并在 2020 年 5 月至 10 月之间进行了一项简短的电话调查，评估了在 COVID-19 大流行期间大麻使用的变化以及整体/心理健康状况，以及对大麻使用的风险/益处的看法。
在大流行期间，整个样本中有 64/222（28.8%）报告大麻使用增加，36/222（16.2%）报告使用减少，122/222（55%）报告没有变化。多变量逻辑回归结果表明：与报告无变化的人相比，大流行期间大麻使用增加与基线时更频繁的大麻使用和 PTSD 症状、大流行期间心理健康恶化以及不认为大麻使用是 COVID-19 感染的危险因素有关。基线时更频繁的大麻使用是与大流行期间大麻使用减少唯一显著相关的因素。
COVID-19 大流行导致相当一部分（45%）PLWH 大麻使用发生变化。需要进一步研究以了解大麻使用增加与心理健康恶化之间的时间关系。
