Post-Graduate Program in Biological Sciences, Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil.
Post-Graduate Program in Food Science and Technology, Department of Food Science and Technology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil.
Neurochem Int. 2021 Sep;148:105085. doi: 10.1016/j.neuint.2021.105085. Epub 2021 May 28.
Nutraceuticals have been the focus of numerous research in recent years and accumulating data support their use for promoting some health benefits. Several nutraceuticals have been widely studied as supplements due to their functional properties ameliorating symptoms associated with neurological disorders, such as oxidative stress and chronic inflammatory states. This seems to be the case of some fruits and seeds from the Amazon Biome consumed since the pre-Columbian period that could have potential beneficial impact on the human nervous system. The beneficial activities of these food sources are possibly related to a large number of bioactive molecules including polyphenols, carotenoids, unsaturated fatty acids, vitamins, and trace elements. In this context, this review compiled the research on six Amazonian fruits and seeds species and some of the major nutraceuticals found in their composition, presenting brief mechanisms related to their protagonist action in improving inflammatory responses and neuroinflammation.
近年来，营养保健品一直是众多研究的焦点，越来越多的数据支持其用于促进某些健康益处。由于具有改善与神经紊乱相关的症状的功能特性，如氧化应激和慢性炎症状态，几种营养保健品已被广泛研究作为补充剂。一些来自亚马逊生物群落的水果和种子似乎就是这种情况，这些水果和种子自哥伦布前时期就被食用，可能对人类神经系统有潜在的有益影响。这些食物来源的有益活动可能与大量生物活性分子有关，包括多酚、类胡萝卜素、不饱和脂肪酸、维生素和微量元素。在这种情况下，本综述汇集了对六种亚马逊水果和种子物种的研究，以及它们成分中发现的一些主要营养保健品，介绍了与其改善炎症反应和神经炎症的主要作用相关的简要机制。
