Guelinckx P J, Faulkner J A, Essig D A
Department of Physiology, University of Michigan, Ann Arbor 48109-0622.
Muscle Nerve. 1988 Jul;11(7):745-51. doi: 10.1002/mus.880110710.
In rabbits, 9 g rectus femoris (RFM) muscles were grafted with tendon repair and with (1) nerves and blood vessels intact, (2) nerves intact and blood vessels anastomosed, or (3) nerves and blood vessels anastomosed. The influences of tendon, nerve, and vascular repair on the functional capabilities of grafts were compared 15-120 days after grafting. Data were collected on the mass, total protein content, oxidative capacity, maximum force development, and fatigability of grafts and control RFM muscles. When stabilized 90-120 days after grafting, mean values for the three types of grafts were not significantly different. Compared with values for control RFM muscles, each type of graft had significantly lower mean values for mass, total protein content, and maximum force, but the grafts were more resistant to fatigue. In RFM grafts, nerve and vascular repair do not contribute significantly to the impairments. Consequently, tendon repair appears to be responsible for the major functional deficits.
在兔子身上，将9克股直肌（RFM）肌肉进行肌腱修复，并分为以下三组进行移植：（1）神经和血管保持完整；（2）神经保持完整，血管进行吻合；（3）神经和血管均进行吻合。在移植后15 - 120天，比较肌腱、神经和血管修复对移植肌肉功能能力的影响。收集了移植肌肉和对照股直肌的质量、总蛋白含量、氧化能力、最大力量发展以及疲劳性的数据。移植后90 - 120天达到稳定状态时，三种移植类型的平均值无显著差异。与对照股直肌的值相比，每种移植类型的质量、总蛋白含量和最大力量的平均值均显著较低，但移植肌肉更耐疲劳。在股直肌移植中，神经和血管修复对功能损伤的影响不显著。因此，肌腱修复似乎是导致主要功能缺陷的原因。
