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ADA 糖尿病风险测试在印度尼西亚成年人群中的适应性:它能否替代随机血糖筛查测试?

ADA Diabetes Risk Test Adaptation in Indonesian Adult Populations: Can It Replace Random Blood Glucose Screening Test?

机构信息

Faculty of Medicine Universitas Indonesia, Central Jakarta, Indonesia.

Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.

出版信息

J Prim Care Community Health. 2021 Jan-Dec;12:21501327211021015. doi: 10.1177/21501327211021015.

Abstract

AIMS

The use of non-invasive and easily available assessment tools such as the ADA diabetes risk test is recommended for diabetes screening among general population. This study aims to assess the validity of the ADA diabetes risk test in screening for screening hyperglycemia in Indonesian population.

METHODS

This cross-sectional study conducted at primary health care in Cibeber sub district at Cilegon city, Banten province, Indonesia. Subjects were aged ≥45 years old without a prior diagnosis of diabetes were recruited consecutively. The risk of hyperglycemia was measured using the ADA Diabetes Risk Test. Random capillary blood glucose (RcBG) with a cut-off value >140 mg/dL used as a comparison.

RESULTS

From a total of 134 subjects, 23.13% of subjects (n = 31) had hyperglycemia. The ADA Diabetes Risk Test gave an area under the ROC curve (AUC) of 0.71 (95% CI: 0.60-0.81) with an optimal cut-off of value ≥5. The sensitivity of the ADA diabetes risk test in diagnosing hyperglycemia was 68% with a false-negative rate (FNR) of 32.26%. Meanwhile, at a cut-off value ≥4, the sensitivity of the ADA Diabetes Risk Test was 93% with an FNR of 9.7%.

CONCLUSION

ADA diabetes risk test provides a valuable result as a diabetes screening tool in the Indonesian population, thus promotes intervention strategies for population known to be at risk.

摘要

目的

建议使用非侵入性和易于获得的评估工具,如 ADA 糖尿病风险测试,对一般人群进行糖尿病筛查。本研究旨在评估 ADA 糖尿病风险测试在印度尼西亚人群中筛查筛查性高血糖的有效性。

方法

这是一项在印度尼西亚万丹省西勒贡市 Cibeber 分区的基层医疗保健机构进行的横断面研究。连续招募年龄≥45 岁且无糖尿病既往诊断的受试者。使用 ADA 糖尿病风险测试测量发生高血糖的风险。随机毛细血管血糖(RcBG)的截断值>140mg/dL 用作比较。

结果

在总共 134 名受试者中,有 23.13%的受试者(n=31)患有高血糖症。ADA 糖尿病风险测试的 ROC 曲线下面积(AUC)为 0.71(95%CI:0.60-0.81),最佳截断值≥5。ADA 糖尿病风险测试诊断高血糖的敏感性为 68%,假阴性率(FNR)为 32.26%。同时,在截断值≥4 时,ADA 糖尿病风险测试的敏感性为 93%,假阴性率为 9.7%。

结论

ADA 糖尿病风险测试为印度尼西亚人群提供了有价值的糖尿病筛查工具结果,从而促进了针对已知高危人群的干预策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0126/8165819/1823892aa95e/10.1177_21501327211021015-fig1.jpg

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