Wang Lixin, Zuo Xu, Ouyang Zhuoer, Qiao Ping, Wang Fang
Department of Cell Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Department of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Evid Based Complement Alternat Med. 2021 May 15;2021:5591573. doi: 10.1155/2021/5591573. eCollection 2021.
Aging is an inevitable stage of body development. At the same time, aging is a major cause of cancer, cardiovascular disease, and neurodegenerative diseases. Chinese herbal medicine is a natural substance that can effectively delay aging and is expected to be developed as antiaging drugs in the future. . This paper reviews the antiaging effects of 23 traditional Chinese herbal medicines or their active components. . We reviewed the literature published in the last five years on Chinese herbal medicines or their active ingredients and their antiaging role obtained through the following databases: PubMed, EMBASE, Scopus, and Web of Science.
A total of 2485 papers were found, and 212 papers were screened after removing the duplicates and reading the titles. Twenty-three studies met the requirements of this review and were included. Among these studies, 13 articles used as the animal model, and 10 articles used other animal models or cell lines.
Chinese herbal medicines or their active components play an antiaging role by regulating genes related to aging through a variety of signaling pathways. Chinese herbal medicines are expected to be developed as antiaging drugs or used in the medical cosmetology industry.
衰老是身体发育不可避免的阶段。同时，衰老是癌症、心血管疾病和神经退行性疾病的主要原因。中草药是一种能有效延缓衰老的天然物质，有望在未来开发成为抗衰老药物。本文综述了23种传统中草药或其活性成分的抗衰老作用。我们通过以下数据库检索了过去五年发表的关于中草药或其活性成分及其抗衰老作用的文献：PubMed、EMBASE、Scopus和Web of Science。
共检索到2485篇论文，去除重复项并阅读标题后筛选出212篇论文。23项研究符合本综述的要求并被纳入。在这些研究中，13篇文章使用了 作为动物模型，10篇文章使用了其他动物模型或细胞系。
中草药或其活性成分通过多种信号通路调节与衰老相关的基因，发挥抗衰老作用。中草药有望开发成为抗衰老药物或应用于医疗美容行业。
