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16种草本植物精油抗炎和免疫调节特性的系统评价

A Systematic Review of the Anti-Inflammatory and Immunomodulatory Properties of 16 Essential Oils of Herbs.

作者信息

Zuo Xu, Gu Yinuo, Wang Chao, Zhang Jinrong, Zhang Jing, Wang Guoqiang, Wang Fang

机构信息

Department of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.

出版信息

Evid Based Complement Alternat Med. 2020 Dec 7;2020:8878927. doi: 10.1155/2020/8878927. eCollection 2020.

Abstract

BACKGROUND

Inflammation is a host defense mechanism in the body after it is infected and damaged. If inflammation is not treated in time, then it may cause a variety of diseases, such as cancer and autoimmune diseases. Herbal essential oils are natural extracts that can suppress inflammation effectively and are expected to be used in therapeutic drugs for anti-inflammatory diseases in the future. . We review the anti-inflammatory and immunomodulatory effects of essential oils derived from 16 herbs. . We searched the literature of the fields of anti-inflammatory and immunomodulatory herbal essential oil activity published in English within the past five years via databases (PubMed, EMBASE, Scopus, and The Web of Science).

RESULTS

A total of 1932 papers were found by searching, and 132 papers were screened after removing duplicates and reading article titles. Fifteen articles met the requirements to be included in this review. Among those selected, 11 articles reported in vivo research results, and 10 articles showed research results.

CONCLUSION

Essential oils extracted from herbs can reduce inflammation by regulating the release of inflammatory cytokines involved in multiple signalling pathways. Herbal essential oils are expected to be developed as anti-inflammatory drugs.

摘要

背景

炎症是机体受到感染和损伤后的一种宿主防御机制。若炎症未得到及时治疗,则可能引发多种疾病,如癌症和自身免疫性疾病。草药精油是能够有效抑制炎症的天然提取物,有望在未来用于抗炎疾病的治疗药物中。我们综述了16种草药精油的抗炎和免疫调节作用。我们通过数据库(PubMed、EMBASE、Scopus和科学网)检索了过去五年内发表的英文抗炎和免疫调节草药精油活性领域的文献。

结果

检索共找到1932篇论文,经去除重复项并阅读文章标题后筛选出132篇论文。15篇文章符合纳入本综述的要求。在所选文章中,11篇报道了体内研究结果,10篇展示了研究成果。

结论

从草药中提取的精油可通过调节参与多种信号通路的炎性细胞因子的释放来减轻炎症。草药精油有望被开发为抗炎药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c9/7735857/fd47bb07ae54/ECAM2020-8878927.001.jpg

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