University of Fortaleza, Fortaleza, Ceará, Brazil.
Department of Restorative Dentistry, Federal University of Ceará, Rua Monsenhor Furtado s/nº, Fortaleza, Ceará, CEP 60430-350, Brazil.
Eur Arch Paediatr Dent. 2021 Oct;22(5):843-849. doi: 10.1007/s40368-021-00636-z. Epub 2021 May 30.
This study sought to evaluate in vitro the effect of a dentifrice containing sodium trimetaphosphate (TMP) combined or not with low fluoride (500 ppm NaF) on dentine erosion of intrinsic origin.
Human root dentine blocks were selected based on surface microhardness and randomly allocated into five groups (n = 12): negative control (0 ppm F; no TMP); F500 (500 ppm NaF); F1500 (1500 ppm NaF-positive control); TMP (1% TMP); and F + TMP (500 ppm NaF + 1% TMP). The blocks were submitted to erosion cycles (3 ×/day) for 3 days (0.01 M HCl, pH 1.5-30 s), treatment (1 min-1:3 p/p dentifrice/distilled water) and remineralization (artificial saliva/120 min). Dentine alterations were determined according to the percentage of microhardness loss (%HL), surface loss (SL) and surface analysis by scanning electron microscopy. The data were analyzed using one-way ANOVA (p < 0.05).
The values of SL and %HL in each group were, respectively: negative control (1.36 ± 0.36; 57.29 ± 14.14), F500 (1.46 ± 0.28; 65.66 ± 5.11), F1500 (1.52 ± 0.36; 61.66 ± 5.15), TMP (1.45 ± 0.45; 62.08 ± 3.83) and F + TMP (1.38 ± 0.42; 63.38 ± 6.47). There was no statistically significant difference in all the parameters (p = 0.873 and p = 0.152).
The dentifrices containing TMP combined or not with fluoride were not able to prevent dentine erosion.
本研究旨在评估含有三聚磷酸钠(TMP)的牙膏单独或与低浓度氟化物(500ppm NaF)联合使用对内在起源牙本质侵蚀的体外影响。
根据表面显微硬度选择人牙根牙本质块,并将其随机分配到五个组(n=12):阴性对照组(0ppm F;无 TMP);F500 组(500ppm NaF);F1500 组(1500ppm NaF-阳性对照组);TMP 组(1% TMP);F+TMP 组(500ppm NaF+1% TMP)。将牙本质块进行侵蚀循环(3×/天,0.01M HCl,pH 1.5-30s),处理(1min-1:3p/p 牙膏/蒸馏水)和再矿化(人工唾液/120min)。根据显微硬度损失百分比(%HL)、表面损失(SL)和扫描电子显微镜表面分析来确定牙本质的变化。采用单因素方差分析(p<0.05)对数据进行分析。
各实验组的 SL 和%HL 值分别为:阴性对照组(1.36±0.36;57.29±14.14)、F500 组(1.46±0.28;65.66±5.11)、F1500 组(1.52±0.36;61.66±5.15)、TMP 组(1.45±0.45;62.08±3.83)和 F+TMP 组(1.38±0.42;63.38±6.47)。所有参数均无统计学差异(p=0.873 和 p=0.152)。
含有 TMP 的牙膏单独或与氟化物联合使用均不能预防牙本质侵蚀。