AlGhamdi Manal, Abdel-Mottaleb Mohamed
Umm Al-Qura University, Department of Computer Science, Saudi Arabia.
University of Miami, Department of Electrical and Computer Engineering, USA.
Comput Methods Programs Biomed. 2021 Aug;207:106152. doi: 10.1016/j.cmpb.2021.106152. Epub 2021 May 11.
Mammography is an X-ray imaging technique used for breast cancer screening. Each breast is usually screened at two different angles generating two views known as mediolateral oblique (MLO) and craniocaudal (CC), which are clinically used by radiologists to detect suspicious masses and diagnose breast cancer. Previous studies applied deep learning models to process each view separately and concatenate the features from the two views to detect and classifying masses. However, direct concatenation is not enough to uncover the relationship between the masses that appear in the two views because they can substantially vary in terms of shape, size, and texture. The relationship between the two views should be established by matching correspondence between their extracted masses. This paper presents a dual-view deep convolutional neural network (DV-DCNN) model for matching masses detected from the two views by establishing correspondence between their extracted patches, which leads to more robust mass detection.
Given a pair of patches as input, the presented model determines whether these patches represent the same mass or not. The network contains two parts: a feature extraction part using tied dense blocks, and a neighborhood patch matching part with three consecutive layers, i.e., a cross-input neighborhood differences layer to find the relationship between the two patches, a patch summary features layer to define a summary of the neighborhood differences and an across-patch features layer to learn a higher-level representation across neighborhood differences.
To evaluate the model's performance in diverse cases, several experimental scenarios were followed for training and testing using two public datasets, i.e., CBIS-DDSM and INbreast. We also evaluate the contribution of our mass-matching model within a mass detection framework. Experiments show that DV-DCNN outperforms other related deep learning models and demonstrate that the detection results improve when using our model.
Matching potential masses between two different views of the same breast leads to more robust mass detection. Experimental results demonstrate the efficacy of a dual-view deep learning model in matching masses, which helps in increasing the accuracy of mass detection and decreasing the false positive rates.
乳腺钼靶摄影是一种用于乳腺癌筛查的X射线成像技术。通常从两个不同角度对每个乳房进行筛查,生成两个视图,即内外斜位(MLO)和头尾位(CC),放射科医生在临床中使用这两个视图来检测可疑肿块并诊断乳腺癌。先前的研究应用深度学习模型分别处理每个视图,并将两个视图的特征连接起来以检测和分类肿块。然而,直接连接不足以揭示在两个视图中出现的肿块之间的关系,因为它们在形状、大小和纹理方面可能有很大差异。应该通过匹配两个视图中提取的肿块之间的对应关系来建立两个视图之间的关系。本文提出了一种双视图深度卷积神经网络(DV-DCNN)模型,通过在提取的补丁之间建立对应关系来匹配从两个视图中检测到的肿块,从而实现更稳健的肿块检测。
给定一对补丁作为输入,所提出的模型确定这些补丁是否代表同一个肿块。该网络包含两个部分:一个使用绑定密集块的特征提取部分,以及一个具有三个连续层的邻域补丁匹配部分,即一个交叉输入邻域差异层以找到两个补丁之间的关系,一个补丁摘要特征层以定义邻域差异的摘要,以及一个跨补丁特征层以跨邻域差异学习更高层次的表示。
为了评估模型在各种情况下的性能,使用两个公共数据集,即CBIS-DDSM和INbreast,遵循了几种实验场景进行训练和测试。我们还评估了我们的肿块匹配模型在肿块检测框架中的贡献。实验表明,DV-DCNN优于其他相关的深度学习模型,并表明使用我们的模型时检测结果会得到改善。
在同一乳房的两个不同视图之间匹配潜在肿块可实现更稳健的肿块检测。实验结果证明了双视图深度学习模型在匹配肿块方面的有效性,这有助于提高肿块检测的准确性并降低假阳性率。