Phan Michael T, Tomaszewski Daniel M, Arbuckle Cody, Yang Sun, Donaldson Candice, Fortier Michelle, Jenkins Brooke, Linstead Erik, Kain Zeev
Chapman University, School of Pharmacy, Irvine, CA, 92618, USA.
Department of Pharmaceutical & Health Economics, University of Southern California, School of Pharmacy, University Park Campus, 635 Downey Way, Bldg. #331, Los Angeles, CA, 90089, USA.
BMC Pediatr. 2021 May 31;21(1):252. doi: 10.1186/s12887-021-02715-y.
Racial/ethnic disparities in the use of opioids to treat pain disorders have been previously reported in the emergency department (ED). Further research is needed to better evaluate the impact race/ethnicity may have on the use of opioids in adolescents for the management of pain disorders in the ED.
This was a cross-sectional study using data from the National Hospital Ambulatory Medical Care Survey from 2006 to 2016. Multivariate models were used to evaluate the role of race/ethnicity in the receipt of opioid agonists while in the ED. All ED visits with patients aged 11-21 years old were analyzed. Races/ethnicities were stratified as non-Hispanic Whites, non-Hispanic Blacks, and Hispanics. In addition to race, statistical analysis included the following covariates: pain score, pain diagnosis, age, region, sex, and payment method.
There was a weighted total of 189,256,419 ED visits. Those visits involved 109,826,315 (58%) non-Hispanic Whites, 46,314,977 (24%) non-Hispanic Blacks, and 33,115,127 (18%) Hispanics, with 21.6% (95% CI, 21.1%-22.1), 15.2% (95% CI, 14.6-15.9%), and 17.4% (95% CI, 16.5-18.2%) of those visits reporting use of opioids, respectively. Regardless of age, sex, and region, non-Hispanic Whites received opioids at a higher rate than non-Hispanic Blacks and Hispanics. Based on diagnosis, non-Hispanic Whites received opioids at a higher rate in multiple pain diagnoses. Additionally, non-Hispanic Blacks and Hispanics were less likely to receive an opioid when reporting moderate pain (aOR = 0.738, 95% CI 0.601-0.906, aOR = 0.739, 95% CI 0.578-0.945, respectively) and severe pain (aOR = 0.580, 95% CI 0.500-0.672, aOR = 0.807, 95% CI 0.685-0.951, respectively) compared to non-Hispanic Whites.
Differences in the receipt of opioid agonists in EDs among the races/ethnicities exist, with more non-Hispanic Whites receiving opioids than their minority counterparts. Non-Hispanic Black women may be an especially marginalized population. Further investigation into sex-based and regional differences are needed.
先前在急诊科(ED)已报道了使用阿片类药物治疗疼痛性疾病方面的种族/民族差异。需要进一步研究以更好地评估种族/民族可能对青少年在急诊科使用阿片类药物治疗疼痛性疾病产生的影响。
这是一项横断面研究,使用了2006年至2016年美国国家医院门诊医疗调查的数据。多变量模型用于评估种族/民族在急诊科接受阿片类激动剂方面的作用。对所有11至21岁患者的急诊科就诊情况进行了分析。种族/民族被分为非西班牙裔白人、非西班牙裔黑人以及西班牙裔。除种族外,统计分析还包括以下协变量:疼痛评分、疼痛诊断、年龄、地区、性别和支付方式。
加权后的急诊科就诊总数为189,256,419次。这些就诊涉及109,826,315名(58%)非西班牙裔白人、46,314,977名(24%)非西班牙裔黑人以及33,115,127名(18%)西班牙裔,其中分别有21.6%(95%置信区间,21.1%-22.1%)、15.2%(95%置信区间,14.6%-15.9%)和17.4%(95%置信区间,16.5%-18.2%)的就诊报告使用了阿片类药物。无论年龄、性别和地区如何,非西班牙裔白人接受阿片类药物的比例高于非西班牙裔黑人和西班牙裔。基于诊断,在多种疼痛诊断中,非西班牙裔白人接受阿片类药物的比例更高。此外,与非西班牙裔白人相比,非西班牙裔黑人和西班牙裔在报告中度疼痛(调整后比值比[aOR]=0.738,95%置信区间0.601-0.906;aOR=0.739,95%置信区间0.578-0.945)和重度疼痛(aOR=0.580,95%置信区间0.500-0.672;aOR=0.807,95%置信区间0.685-0.951)时接受阿片类药物的可能性较小。
不同种族/民族在急诊科接受阿片类激动剂方面存在差异,非西班牙裔白人接受阿片类药物的人数多于少数族裔。非西班牙裔黑人女性可能是一个特别边缘化的群体。需要进一步调查基于性别的差异和地区差异。