Department of Biosciences, Manipal University Jaipur, Rajasthan, 303007, Jaipur, India.
Folia Microbiol (Praha). 2021 Aug;66(4):483-507. doi: 10.1007/s12223-021-00875-z. Epub 2021 May 31.
Myxobacteria belong to a group of bacteria that are known for their well-developed communication system and synchronized or coordinated movement. This typical behavior of myxobacteria is mediated through secondary metabolites. They are capable of producing secondary metabolites belonging to several chemical classes with unique and wide spectrum of bioactivities. It is predominantly significant that myxobacteria specialize in mechanisms of action that are very rare with other producers. Most of the metabolites have been explored for their medical and pharmaceutical values while a lot of them are still unexplored. This review is an attempt to understand the role of potential metabolites produced by myxobacteria in different applications. Different myxobacterial metabolites have demonstrated antibacterial, antifungal, and antiviral properties along with cytotoxic activity against various cell lines. Beside their metabolites, these myxobacteria have also been discussed for better exploitation and implementation in different industrial sectors.
粘细菌属于一类以其发达的通讯系统和同步或协调运动而闻名的细菌。粘细菌的这种典型行为是通过次级代谢物介导的。它们能够产生属于几种化学类别的次级代谢物，具有独特而广泛的生物活性。值得注意的是，粘细菌专门从事其他生产者很少采用的作用机制。大多数代谢产物因其医学和药物价值而被探索，而许多代谢产物仍未被探索。本综述旨在了解粘细菌产生的潜在代谢物在不同应用中的作用。不同的粘细菌代谢产物表现出抗菌、抗真菌和抗病毒特性，以及对各种细胞系的细胞毒性活性。除了它们的代谢产物，这些粘细菌也被讨论用于在不同的工业领域更好地开发和实施。
