Matsumoto T, Aizawa O
Atomic Energy Research Laboratory, Musashi Institute of Technology, Kawasaki-shi, Japan.
Phys Med Biol. 1988 Jun;33(6):671-86. doi: 10.1088/0031-9155/33/6/002.
Head phantom experiments with various neutron beams and calculations were carried out in order to provide useful information for boron neutron capture therapy (BNCT). Thermal neutron beams for thermal neutron capture therapy were used for phantom experiments with various neutron collimator aperture sizes. The filtered beam neutrons of 24 and 144 keV generated with iron and silicon filters were also used to investigate the possible application of BNCT in the treatment of deep-seated cancers. Thermal neutron fluence and induced capture gamma dose distributions within the phantom were calculated with a transport code DOT 3.5 and compared with the experimental results. The results showed that the calculation used was consistent with the experimental results and provided useful information on BNCT. The filtered beam neutron may be very useful for the treatment of deep or widespread cancer, if there were a high power research reactor constructed for this purpose.
为了为硼中子俘获疗法（BNCT）提供有用信息，开展了使用各种中子束的头部模体实验及相关计算。用于热中子俘获疗法的热中子束被用于不同中子准直器孔径尺寸的模体实验。还用铁和硅滤片产生的24 keV和144 keV的滤波束中子来研究BNCT在治疗深部癌症方面的可能应用。用输运代码DOT 3.5计算了模体内的热中子注量和诱导俘获伽马剂量分布，并与实验结果进行了比较。结果表明，所采用的计算与实验结果一致，并为BNCT提供了有用信息。如果为此建造一个高功率研究反应堆，滤波束中子可能对治疗深部或广泛癌症非常有用。
