NIDA-IRP.
Behav Neurosci. 2021 Apr;135(2):267-276. doi: 10.1037/bne0000463.
Theories of orbitofrontal cortex (OFC) function have evolved substantially over the last few decades. There is now a general consensus that the OFC is important for predicting aspects of future events and for using these predictions to guide behavior. Yet the precise content of these predictions and the degree to which OFC contributes to agency contingent upon them has become contentious, with several plausible theories advocating different answers to these questions. In this review we will focus on three of these ideas-the economic value, credit assignment, and cognitive map hypotheses-describing both their successes and failures. We will propose that these failures hint at a more nuanced and perhaps unique role for the OFC, particularly the lateral subdivision, in supporting the proposed functions when an underlying model or map of the causal structures in the environment must be constructed or updated. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
过去几十年来,眶额皮层(OFC)功能的理论已经有了很大的发展。现在人们普遍认为,OFC 对于预测未来事件的各个方面以及利用这些预测来指导行为非常重要。然而,这些预测的确切内容以及 OFC 在多大程度上取决于这些预测来发挥作用,已经引起了争议,有几个合理的理论对这些问题提出了不同的答案。在这篇综述中,我们将重点介绍其中三个观点,即经济价值、信用分配和认知地图假说,描述它们的成功和失败。我们将提出,这些失败表明,当必须构建或更新环境中因果结构的基础模型或地图时,OFC(特别是外侧部分)在支持这些功能方面可能具有更微妙、也许是独特的作用。