Wen Sijin, Prasad Apoorv, Freeland Kerri, Podury Sanjiti, Patel Jenil, Subedi Roshan, Khan Erum, Tandon Medha, Kataria Saurabh, Kimble Wesley, Sriwastava Shitiz
Department of Biostatistics, West Virginia University, Morgantown, WV 26505, USA.
Berkeley Medical Center, Department of Neurology, West Virginia University, Morgantown, WV 25401, USA.
Viruses. 2021 May 5;13(5):835. doi: 10.3390/v13050835.
This study examines the clinical characteristics, outcomes and types of management in SARS-CoV-2 infected patients, in the hospitals affiliated with West Virginia University. We included patients from West Virginia with SARS-CoV-2 infection between 15 April to 30 December 2020. Descriptive analysis was performed to summarize the characteristics of patients. Regression analyses were performed to assess the association between baseline characteristics and outcomes. Of 1742 patients, the mean age was 47.5 years (±22.7) and 54% of patients were female. Only 459 patients (26.3%) reported at least one baseline symptom, of which shortness of breath was most common. More than half had at least one comorbidity, with hypertension being the most common. There were 131 severe cases (7.5%), and 84 patients (4.8%) died despite treatment. The mean overall length of hospital stay was 2.6 days (±6.9). Age, male sex, and comorbidities were independent predictors of outcomes. In this study of patients with SARS-CoV-2 infection from West Virginia, older patients with underlying co-morbidities had poor outcomes, and the in-hospital mortality was similar to the national average.
本研究调查了西弗吉尼亚大学附属医院中感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）患者的临床特征、治疗结果及管理类型。我们纳入了2020年4月15日至12月30日期间来自西弗吉尼亚州的SARS-CoV-2感染患者。进行描述性分析以总结患者特征。进行回归分析以评估基线特征与治疗结果之间的关联。在1742名患者中，平均年龄为47.5岁（±22.7），54%的患者为女性。只有459名患者（26.3%）报告至少有一种基线症状，其中呼吸急促最为常见。超过一半的患者至少有一种合并症，高血压最为常见。有131例重症病例（7.5%），84名患者（4.8%）尽管接受了治疗仍死亡。平均住院总时长为2.6天（±6.9）。年龄、男性性别和合并症是治疗结果的独立预测因素。在这项对来自西弗吉尼亚州的SARS-CoV-2感染患者的研究中，有基础合并症的老年患者治疗结果较差，住院死亡率与全国平均水平相似。
