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双刃剑:日间小睡时长与中国人群代谢相关疾病的关联。

A double-edged sword: the association of daytime napping duration and metabolism related diseases in a Chinese population.

机构信息

Chronic Disease Research Institute, the Children's Hospital, and National Clinical Research Center for Child Health, School of Public Health, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Department of Nutrition and Food Hygiene, School of Public Health, Zhejiang University, Hangzhou, Zhejiang, China.

出版信息

Eur J Clin Nutr. 2021 Feb;75(2):291-298. doi: 10.1038/s41430-020-00777-2. Epub 2020 Oct 20.

Abstract

BACKGROUND

Some studies have suggested that daytime napping may increase the risk of type 2 diabetes. However, limited data have revealed the association between nap duration and other metabolic diseases. Data from the baseline survey of Lanxi Cohort Study, a population-based study of natural residents in Zhejiang Province, China, were used to investigate the relationship between nap duration and metabolic abnormalities.

METHODS

A total of 3236 participants underwent a physical examination, laboratory tests, and face to face interview. They were categorized into four groups according to nap duration. Logistic regression models were used to examine the odds ratios (ORs) of napping duration with four metabolism-related diseases. Stratified analysis was further used to explore the interaction effects of gender and age on results.

RESULTS

Compared to the no daytime napping group, people who napped during the daytime for more than 1 h were independently associated with a greater prevalence of diabetes (OR 1.56). Those who napped during the daytime within a half hour showed a lower prevalence of fatty liver, dyslipidemia, and central obesity. To be more specific, those who habitually napped during the daytime for more than 1 h exhibited an increasing prevalence of diabetes among female older than 50 years old. Those who habitually napped during the daytime within a half hour exhibited a decreasing prevalence of fatty liver and dyslipidemia among male <50 years old, and that of central obesity among female <50 years old.

CONCLUSIONS

Short daytime napping duration is associate with reduced rate of metabolism-related diseases and may protects people from negative health conditions, whereas long daytime napping duration is associate with higher prevalence of diabetes, which then can be harmful for health.

摘要

背景

一些研究表明,白天小睡可能会增加 2 型糖尿病的风险。然而,有限的数据揭示了小睡持续时间与其他代谢疾病之间的关联。本研究使用来自中国浙江省自然居民的基于人群的兰溪市队列研究的基线调查数据,调查了小睡持续时间与代谢异常之间的关系。

方法

共有 3236 名参与者接受了体检、实验室检查和面对面访谈。他们根据小睡持续时间分为四组。使用逻辑回归模型检查与四种代谢相关疾病相关的小睡持续时间的比值比(OR)。进一步进行分层分析以探讨性别和年龄对结果的交互作用。

结果

与没有白天小睡的组相比,白天小睡超过 1 小时的人独立与糖尿病(OR 1.56)的患病率增加相关。白天小睡半小时内的人患脂肪肝、血脂异常和中心性肥胖的患病率较低。更具体地说,50 岁以上女性习惯性白天小睡超过 1 小时者,糖尿病患病率增加;50 岁以下男性习惯性白天小睡半小时内者,脂肪肝和血脂异常的患病率降低,50 岁以下女性习惯性白天小睡半小时内者,中心性肥胖的患病率降低。

结论

白天小睡持续时间较短与代谢相关疾病的发生率降低有关,可能有助于保护人们免受不良健康状况的影响,而白天小睡持续时间较长与糖尿病的高患病率有关,这可能对健康有害。

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