O'Heany J, Kusiak R, Duncan C E, Smith J F, Smith L F, Spielberg L
Ontario Ministry of Labour, Special Studies and Services, Toronto, Canada.
Sci Total Environ. 1988 Jun 1;71(3):477-83. doi: 10.1016/0048-9697(88)90221-5.
The purpose of this study was to determine blood levels in Ontario children and to identify those risk factors associated with higher blood lead levels. A random sample of 1315 children aged 7 and younger from urban, suburban and rural Ontario was selected. Blood lead concentration was determined in finger prick blood samples by graphite furnace atomic absorption spectrophotometry. Measurements of lead in air, tap water, soil, and gasoline were also established. Traffic pattern were determined in each area. A questionnaire was administered to a random sample of 800 families of the children tested to assess the presence of other risk factors. Urban children had higher geometric mean blood lead levels (12.02, S.D. = 4.4 micrograms/dl) than suburban children (9.95, S.D. = 3.5 micrograms/dl), and they, in turn, had higher blood lead levels than rural children (8.91, S.D. = 3.9 micrograms/dl). Each of these differences is statistically significant (p less than 0.001). Fifty four (4.3%) of all children were at or above the alert level of 20 micrograms/dl. The proportion above the alert level did not differ significantly between urban, suburban and rural children. Blood lead levels were slightly higher for males than females and for pre-schoolers aged 3 and 4, compared to school age children aged 5 and 6. The blood lead levels of these children were significantly lower than that of children surveyed near a point source of industrial emissions. Multivariate statistical modelling resulted in a set of characteristics which best explained the differences in children's blood lead levels.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是测定安大略省儿童的血铅水平,并确定与较高血铅水平相关的风险因素。从安大略省的城市、郊区和农村随机抽取了1315名7岁及以下儿童作为样本。通过石墨炉原子吸收分光光度法测定手指刺血样本中的血铅浓度。还对空气、自来水、土壤和汽油中的铅含量进行了测量。确定了每个区域的交通模式。对随机抽取的800名受试儿童家庭进行问卷调查,以评估其他风险因素的存在情况。城市儿童的几何平均血铅水平(12.02,标准差=4.4微克/分升)高于郊区儿童(9.95,标准差=3.5微克/分升),而郊区儿童又高于农村儿童(8.91,标准差=3.9微克/分升)。这些差异均具有统计学意义(p<0.001)。所有儿童中有54名(4.3%)血铅水平达到或超过20微克/分升的警戒水平。城市、郊区和农村儿童中高于警戒水平的比例没有显著差异。男性儿童和3、4岁学龄前儿童的血铅水平略高于5、6岁学龄儿童。这些儿童的血铅水平显著低于在工业排放点源附近接受调查的儿童。多变量统计建模得出了一组最能解释儿童血铅水平差异的特征。(摘要截短于250字)