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基于海藻酸盐的生物材料的制备及其在生物医学中的应用。

Preparation of Alginate-Based Biomaterials and Their Applications in Biomedicine.

机构信息

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.

NMPA Key Laboratory for Quality Research and Control of Tissue Regenerative Biomaterial, Institute of Regulatory Science for Medical Devices, NMPA Research Base of Regulatory Science for Medical Devices, Sichuan University, Chengdu 610064, China.

出版信息

Mar Drugs. 2021 May 10;19(5):264. doi: 10.3390/md19050264.

DOI:10.3390/md19050264
PMID:34068547
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8150954/
Abstract

Alginates are naturally occurring polysaccharides extracted from brown marine algae and bacteria. Being biocompatible, biodegradable, non-toxic and easy to gel, alginates can be processed into various forms, such as hydrogels, microspheres, fibers and sponges, and have been widely applied in biomedical field. The present review provides an overview of the properties and processing methods of alginates, as well as their applications in wound healing, tissue repair and drug delivery in recent years.

摘要

藻酸盐是从褐藻和细菌中提取的天然多糖。藻酸盐具有生物相容性、可生物降解、无毒和易于凝胶化等特点,可以加工成各种形式,如水凝胶、微球、纤维和海绵,并已广泛应用于生物医学领域。本文综述了藻酸盐的性质和加工方法,以及近年来在创伤愈合、组织修复和药物传递中的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b22/8150954/6e93d204f402/marinedrugs-19-00264-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b22/8150954/c2f9925c9d23/marinedrugs-19-00264-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b22/8150954/e50a6ce08ed3/marinedrugs-19-00264-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b22/8150954/2fdd25d25c79/marinedrugs-19-00264-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b22/8150954/6e93d204f402/marinedrugs-19-00264-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b22/8150954/c2f9925c9d23/marinedrugs-19-00264-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b22/8150954/e50a6ce08ed3/marinedrugs-19-00264-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b22/8150954/2fdd25d25c79/marinedrugs-19-00264-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b22/8150954/6e93d204f402/marinedrugs-19-00264-g004.jpg

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