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用于骨感染的医用生物材料的研究进展

Research Progress in Medical Biomaterials for Bone Infections.

作者信息

Lian Tianxu, Wang Yiwei, Zheng Pengfei

机构信息

Department of Orthopaedics Surgery, Children's Hospital of Nanjing Medical University, Nanjing 210029, China.

出版信息

J Funct Biomater. 2025 May 21;16(5):189. doi: 10.3390/jfb16050189.

Abstract

Bone infection is a debilitating condition characterized by inflammation of the bone and its marrow. It poses significant challenges in clinical practice due to its recalcitrant nature and difficulty in eradicating the infecting microorganisms. Recent advancements in the field of medical biomaterials have shown hope in the treatment of bone infections. This article reviews the research progress of medical biomaterials for anti-osteomyelitis in recent years, focusing on the mechanism of action, unique advantages, and application backgrounds of various materials. At the same time, we pay attention to the need for materials used in the treatment of osteomyelitis to promote bone healing.

摘要

骨感染是一种使人衰弱的病症,其特征为骨及其骨髓的炎症。由于其顽固的性质以及难以根除感染微生物,它在临床实践中带来了重大挑战。医用生物材料领域的最新进展为骨感染的治疗带来了希望。本文综述了近年来用于抗骨髓炎的医用生物材料的研究进展,重点关注各种材料的作用机制、独特优势和应用背景。同时,我们关注治疗骨髓炎所用材料促进骨愈合的需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdb9/12111946/f47261988be3/jfb-16-00189-g001.jpg

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