Department of Food and Nutrition, Institute of Home Economics, F-4 Hauz Khas Enclave, New Delhi, 1100016, India.
Department of Food and Nutrition, Institute of Home Economics, F-4 Hauz Khas Enclave, New Delhi, 1100016, India; Department of Food and Nutrition, University of Delhi, India.
Biomed Pharmacother. 2018 Jun;102:575-586. doi: 10.1016/j.biopha.2018.03.023. Epub 2018 Apr 5.
Hibiscus sabdariffa L. (roselle) belonging to the Malvaceae family is widely grown in many countries. This plant is often used in the traditional medicine being rich in phytochemicals like polyphenols especially anthocyanins, polysaccharides and organic acids thus having enormous prospective in modern therapeutic uses. The study aimed to review and document all the available evidence and information about the calyces of Hibiscus sabdariffa (roselle) with the special focus on their nutritional composition, bioactive constituents and therapeutic uses. The electronic database was searched up to 2017, using keywords Hibiscus sabdariffa, chemical constituents of roselle, therapeutic uses of roselle. Journals, books and conference proceedings were also searched. The review provides valuable information about the nutraceutical component of Hibiscus sabdariffa L. and their utilization for curing various degenerative diseases like hypertension, hyperlipidemia, cancer and other inflammatory diseases of liver and kidney. Their toxicological effects have also been discussed from a safety point of view. Most studies supported and provided the scientific basis for the statement that Hibiscus sabdariffa and their active constituents play an important role in the prevention of chronic and degenerative diseases that are associated with oxidative stress. Our study suggests, that good research is needed, to establish a potential strategy that can balance the pharmacological and toxic effects of roselle and standardized fingerprint of Hibiscus sabdariffa is required internationally for quality control.
洛神花（玫瑰茄）属于锦葵科，广泛生长在许多国家。这种植物经常被应用于传统医学，因为它富含多种植物化学物质，如多酚类物质，特别是花色苷、多糖和有机酸，因此在现代治疗用途中有巨大的发展潜力。本研究旨在综述和记录所有关于洛神花（玫瑰茄）花萼的现有证据和信息，特别关注其营养成分、生物活性成分和治疗用途。使用关键词“洛神花”、“玫瑰茄的化学成分”、“玫瑰茄的治疗用途”对电子数据库进行了搜索，检索时间截至 2017 年。还对期刊、书籍和会议论文集进行了搜索。该综述提供了关于洛神花（玫瑰茄）营养成分的有价值信息，及其用于治疗各种退行性疾病的用途，如高血压、高血脂、癌症和肝脏、肾脏的其他炎症性疾病。还从安全角度讨论了其毒理学效应。大多数研究都支持并为以下说法提供了科学依据，即洛神花及其活性成分在预防与氧化应激相关的慢性和退行性疾病方面发挥着重要作用。我们的研究表明，需要进行良好的研究，以确定一种潜在的策略，可以平衡洛神花的药理和毒理作用，并且需要在国际上建立洛神花的标准化指纹图谱，以进行质量控制。
