Haswell Cameron, Ali Ajmol, Page Rachel, Hurst Roger, Rutherfurd-Markwick Kay
School of Health Sciences, Massey University, Auckland 0745, New Zealand.
School of Sport, Exercise and Nutrition, Massey University, Auckland 0745, New Zealand.
Metabolites. 2021 May 25;11(6):338. doi: 10.3390/metabo11060338.
Metabolic syndrome (MetS) is a group of metabolic abnormalities, which together lead to increased risk of coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM), as well as reduced quality of life. Dietary nitrate, betalains and anthocyanins may improve risk factors for MetS and reduce the risk of development of CHD and T2DM. Beetroot is a rich source of dietary nitrate, and anthocyanins are present in high concentrations in blackcurrants. This narrative review considers the efficacy of beetroot and blackcurrant compounds as potential agents to improve MetS risk factors, which could lead to decreased risk of CHD and T2DM. Further research is needed to establish the mechanisms through which these outcomes may occur, and chronic supplementation studies in humans may corroborate promising findings from animal models and acute human trials.
代谢综合征(MetS)是一组代谢异常,这些异常共同导致冠心病(CHD)和2型糖尿病(T2DM)风险增加,以及生活质量下降。膳食硝酸盐、甜菜色素和花青素可能改善代谢综合征的风险因素,并降低冠心病和2型糖尿病的发病风险。甜菜根是膳食硝酸盐的丰富来源,黑加仑中花青素含量很高。这篇叙述性综述探讨了甜菜根和黑加仑中的化合物作为改善代谢综合征风险因素的潜在药物的功效,这可能会降低冠心病和2型糖尿病的风险。需要进一步研究来确定这些结果可能发生的机制,对人类的长期补充研究可能会证实动物模型和人体急性试验中的有前景的发现。