Government Department of School Education, Jammu 180001, Jammu and Kashmir, India.
Vatsalya Clinic, Krishna Nagar, New Delhi 110051, Delhi, India.
Cells. 2021 May 23;10(6):1296. doi: 10.3390/cells10061296.
From time immemorial, humans have exploited plants as a source of food and medicines. The World Health Organization (WHO) has recorded 21,000 plants with medicinal value out of 300,000 species available worldwide. The promising modern "multi-omics" platforms and tools have been proven as functional platforms able to endow us with comprehensive knowledge of the proteome, genome, transcriptome, and metabolome of medicinal plant systems so as to reveal the novel connected genetic (gene) pathways, proteins, regulator sequences and secondary metabolite (molecule) biosynthetic pathways of various drug and protein molecules from a variety of plants with therapeutic significance. This review paper endeavors to abridge the contemporary advancements in research areas of multi-omics and the information involved in decoding its prospective relevance to the utilization of plants with medicinal value in the present global scenario. The crosstalk of medicinal plants with genomics, transcriptomics, proteomics, and metabolomics approaches will be discussed.
自古以来，人类就一直利用植物作为食物和药物的来源。世界卫生组织（WHO）记录了全球 30 万种植物中有 21000 种具有药用价值。有前途的现代“多组学”平台和工具已被证明是功能平台，能够为我们提供药用植物系统的蛋白质组、基因组、转录组和代谢组的全面知识，从而揭示新型连接的遗传（基因）途径、蛋白质、调节剂序列和各种具有治疗意义的植物中各种药物和蛋白质分子的次生代谢（分子）生物合成途径。本文旨在简述多组学研究领域的当代进展，以及解码其与当前全球背景下利用具有药用价值的植物相关的潜在相关性的信息。本文还将讨论药用植物与基因组学、转录组学、蛋白质组学和代谢组学方法的相互作用。
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