Becskereki Gergely, Horvai George, Tóth Blanka
Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, Szent Gellert ter 4., H-1111 Budapest, Hungary.
Polymers (Basel). 2021 May 28;13(11):1781. doi: 10.3390/polym13111781.
The general claim about novel molecularly imprinted polymers is that they are selective for their template or for another target compound. This claim is usually proved by some kind of experiment, in which a performance parameter of the imprinted polymer is shown to be better towards its template than towards interferents. A closer look at such experiments shows, however, that different experiments may differ substantially in what they tell about the same imprinted polymer's selectivity. Following a short general discussion of selectivity concepts, the selectivity of imprinted polymers is analyzed in batch adsorption, binding assays, chromatography, solid phase extraction, sensors, membranes, and catalysts. A number of examples show the problems arising with each type of application. Suggestions for practical method design are provided.
关于新型分子印迹聚合物的一般说法是，它们对其模板或另一种目标化合物具有选择性。这一说法通常通过某种实验来证明，在该实验中，印迹聚合物的性能参数对其模板的表现优于对干扰物的表现。然而，仔细研究此类实验会发现，不同实验对于同一印迹聚合物选择性的说明可能存在很大差异。在对选择性概念进行简短的一般性讨论之后，对印迹聚合物在批量吸附、结合测定、色谱法、固相萃取、传感器、膜和催化剂中的选择性进行了分析。大量实例展示了每种应用类型所产生的问题。并提供了实际方法设计的建议。
