通过磁共振成像（MRI）研究精神分裂症的脑形态学。
Brain morphology in schizophrenia by magnetic resonance imaging (MRI).
作者信息
Rossi A, Stratta P, Gallucci M, Passariello R, Casacchia M
机构信息
Department of Internal Medicine, S. Maria di Collemaggio Hospital, University of L'Aquila, Italy.
出版信息
Acta Psychiatr Scand. 1988 Jun;77(6):741-5. doi: 10.1111/j.1600-0447.1988.tb05197.x.
We report an in vivo Magnetic Resonance Imaging (MRI) Study of the brain in male schizophrenics and individually matched controls. Due to the multiplanar imaging capabilities of MRI we have obtained both midsagittal and axial scans. On the axial plane schizophrenics showed a significant increase of Ventricular Brain Ratio and on the sagittal plane a significant reduction of corpus callosum to brain ratio. In a factor analysis these two abnormalities loaded on components statistically independent suggesting different dimension of brain pathology in schizophrenia.
我们报告了一项针对男性精神分裂症患者及个体匹配对照者大脑的活体磁共振成像（MRI）研究。由于MRI具有多平面成像能力，我们获得了正中矢状面和轴面扫描图像。在轴面上，精神分裂症患者的脑室脑比率显著增加；在矢状面上，胼胝体与脑的比率显著降低。在一项因子分析中，这两种异常情况加载在统计上相互独立的成分上，表明精神分裂症中大脑病理学存在不同维度。
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