Ogita S, Mizuno M, Takeda Y, Arai M, Sugawa T, Kuwabara Y, Hashimoto T, Nishijima M, Imanaka M
Osaka City Perinatal Center, Japan.
Am J Obstet Gynecol. 1988 Aug;159(2):336-41. doi: 10.1016/s0002-9378(88)80080-2.
The aim of this multiinstitutional study was to evaluate a new cervical indwelling catheter in 84 patients with premature rupture of the membranes at less than 33 weeks' gestation. The average time of insertion of the catheter was 29.1 weeks' gestation, at an average of 2.0 days after rupture, and was left in place for an average of 6.5 days. The mean birth weight was 1417 gm. The mortality rate and the incidence of respiratory distress syndrome were 5.7% and 11.9%, respectively. Amniotic fluid culture was positive in 39.1% of patients before catheter insertion and only 4.3% at the time of delivery. Infection was noted in only four of 84 infants. The incidence of infection was very low in those treated for 3 days or more after catheter insertion.
这项多机构研究的目的是评估一种新型宫颈留置导管在84例妊娠小于33周胎膜早破患者中的应用情况。导管插入的平均孕周为29.1周，平均在胎膜破裂后2.0天插入，平均留置6.5天。平均出生体重为1417克。死亡率和呼吸窘迫综合征的发生率分别为5.7%和11.9%。39.1%的患者在导管插入前羊水培养呈阳性，而在分娩时仅为4.3%。84例婴儿中仅4例出现感染。在导管插入后治疗3天或更长时间的患者中，感染发生率非常低。
