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Reduced Proportion and Activity of Natural Killer Cells in the Lung of Patients with Idiopathic Pulmonary Fibrosis.

作者信息

Cruz Tamara, Jia Minxue, Sembrat John, Tabib Tracy, Agostino Naomi, Bruno Tullia C, Vignali Dario, Sanchez Pablo, Lafyatis Robert, Mora Ana L, Benos Panayiotis, Rojas Mauricio

机构信息

University of Pittsburgh Pittsburgh, Pennsylvania.

Carnegie Mellon University Pittsburgh, Pennsylvania.

出版信息

Am J Respir Crit Care Med. 2021 Sep 1;204(5):608-610. doi: 10.1164/rccm.202012-4418LE.

DOI:10.1164/rccm.202012-4418LE
PMID:34077698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8491266/
Abstract
摘要

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本文引用的文献

1
Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK CD8 T Cells as Conserved Hallmark of Inflammaging.全面分析衰老免疫系统揭示克隆性 GZMK CD8 T 细胞是炎症衰老的保守标志。
Immunity. 2021 Jan 12;54(1):99-115.e12. doi: 10.1016/j.immuni.2020.11.005. Epub 2020 Dec 2.
2
Multi-level immune response network in mild-moderate Chronic Obstructive Pulmonary Disease (COPD).轻度-中度慢性阻塞性肺疾病(COPD)中的多层次免疫反应网络。
Respir Res. 2019 Jul 12;20(1):152. doi: 10.1186/s12931-019-1105-z.
3
Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis.特发性肺纤维化中增殖的 SPP1/MERTK 表达巨噬细胞。
Eur Respir J. 2019 Aug 22;54(2). doi: 10.1183/13993003.02441-2018. Print 2019 Aug.
4
The IL-15-AKT-XBP1s signaling pathway contributes to effector functions and survival in human NK cells.IL-15-AKT-XBP1s 信号通路有助于人类自然杀伤细胞的效应功能和存活。
Nat Immunol. 2019 Jan;20(1):10-17. doi: 10.1038/s41590-018-0265-1. Epub 2018 Dec 10.
5
Cellular senescence mediates fibrotic pulmonary disease.细胞衰老介导肺纤维化疾病。
Nat Commun. 2017 Feb 23;8:14532. doi: 10.1038/ncomms14532.
6
Location and cellular stages of natural killer cell development.自然杀伤细胞发育的位置和细胞阶段。
Trends Immunol. 2013 Dec;34(12):573-82. doi: 10.1016/j.it.2013.07.005. Epub 2013 Sep 19.
7
The impact of ageing on natural killer cell function and potential consequences for health in older adults.衰老对自然杀伤细胞功能的影响及其对老年人健康的潜在影响。
Ageing Res Rev. 2013 Sep;12(4):1069-78. doi: 10.1016/j.arr.2013.04.003. Epub 2013 May 6.
8
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.衰老监控良性前肝癌细胞可限制肝癌发生。
Nature. 2011 Nov 9;479(7374):547-51. doi: 10.1038/nature10599.
9
An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management.特发性肺纤维化:诊断和管理的循证指南(美国胸科学会/欧洲呼吸学会/日本呼吸学会/拉丁美洲胸科学会联合发布)
Am J Respir Crit Care Med. 2011 Mar 15;183(6):788-824. doi: 10.1164/rccm.2009-040GL.
10
Metallothionein and the biology of aging.金属硫蛋白与衰老生物学。
Ageing Res Rev. 2011 Jan;10(1):132-45. doi: 10.1016/j.arr.2010.09.007. Epub 2010 Oct 8.