Department of Respiratory and Critical Care Medicine, Fuzhou Pulmonary Hospital of Fujian, Educational Hospital of Fujian Medical University, Fuzhou, China.
Department of Clinical Laboratory, Fuzhou Pulmonary Hospital of Fujian, Educational Hospital of Fujian Medical University, Fuzhou, China.
J Clin Lab Anal. 2021 Jul;35(7):e23811. doi: 10.1002/jcla.23811. Epub 2021 Jun 3.
To explore the clinical manifestation, imaging examination, and serology of patients with novel coronavirus pneumonia (COVID-19) between China and overseas.
Ninety patients with COVID-19 who admitted to Fuzhou Pulmonary Hospital from January 23, 2020, to May 1, 2020, were included in this retrospective study. They were divided into domestic group and overseas group according to the origin regions. The clinical manifestations, imaging examination, serology, treatment, and prognosis between the two groups were compared and analyzed.
The clinical manifestations of patients in the two groups mainly included fever (83.1% and 47.4%), cough (62% and 31.6%), expectoration (47.9% and 31.6%), anorexia (28.2% and 47.4%), fatigue (21.1% and 10.5%), and dyspnea (22.5% and 0%). The main laboratory characteristics in the two groups were decreased lymphocyte count, increased lactate dehydrogenase, decreased oxygenation index, decreased white blood cell count, increased erythrocyte sedimentation rate (ESR), and increased C-reactive protein. The computed tomography (CT) examinations of chest showed bilateral and peripheral involvement, with multiple patch shadows and ground glass shadows. However, pleural effusions were rare.
Fever, cough, and dyspnea are more common in domestic cases than overseas cases. However, patients with COVID-19 from overseas may have the symptoms of loss of taste and smell that domestic cases do not have.
探讨中国和国外新型冠状病毒肺炎(COVID-19)患者的临床表现、影像学检查和血清学特点。
回顾性分析 2020 年 1 月 23 日至 5 月 1 日收治于福州肺科医院的 90 例 COVID-19 患者的临床资料,根据发病地区分为国内组和国外组,比较并分析两组患者的临床表现、影像学检查、血清学、治疗及转归情况。
两组患者的临床表现主要为发热(83.1%比 47.4%)、咳嗽(62%比 31.6%)、咳痰(47.9%比 31.6%)、纳差(28.2%比 47.4%)、乏力(21.1%比 10.5%)、呼吸困难(22.5%比 0%)。两组患者实验室特点主要为淋巴细胞计数减少、乳酸脱氢酶升高、氧合指数降低、白细胞计数减少、红细胞沉降率(ESR)升高、C 反应蛋白升高。胸部 CT 检查均表现为双肺外周及多叶病变,以斑片状及磨玻璃影为主,胸腔积液少见。
国内 COVID-19 患者以发热、咳嗽、呼吸困难为主要表现,国外 COVID-19 患者味觉、嗅觉丧失的发生率可能高于国内患者。