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法罗群岛成年人口的碘营养状况:一项基于人群的研究。

Iodine nutrition among the adult population of the Faroe Islands: a population-based study.

机构信息

Department of Endocrinology and Medicine, The National Hospital of the Faroe Islands, Tórshavn, Faroe Islands.

Center of Health Science, University of the Faroe Islands, Tórshavn, Faroe Islands.

出版信息

Br J Nutr. 2022 Apr 28;127(8):1190-1197. doi: 10.1017/S0007114521001938. Epub 2021 Jun 4.

Abstract

The WHO recommends monitoring iodine status in all populations with median urinary iodine concentration (UIC) below 100 µg/l suggesting iodine deficiency. There are no data on the iodine intake among the population of the Faroe Islands. This study aimed to provide data on iodine nutrition in a representative sample of the general adult population from the Faroe Islands. We conducted a population-based cross-sectional survey in 2011-2012 and measured iodine in urine from 491 participants (294/197 men/women) using the ceri/arsen method after alkaline ashing. Participants include about 100 subjects in each of four adult decades and included participants from both the capital city and villages. The median UIC was low within the recommended range 101 µg/l (range 21-1870 µg/l). No samples were in the range suggesting severe iodine deficiency, but half of the samples were in the range of just adequate or mildly insufficient iodine intake with UIC markedly lower in women than in men (86 v. 115 µg/l; P < 0·001). Intake of fish and whale meals affected the UIC. In conclusion, nearly half of the population had an iodine excretion in the range of borderline or mild iodine deficiency. The lowest iodine nutrition level among Faroese women is a concern as it may extend to pregnancy with increased demands on iodine nutrition. In addition, we found that large variations and the intermittently excessive iodine intakes warrant follow-up on thyroid function in the population of the Faroe Islands.

摘要

世界卫生组织建议监测所有尿碘中位数(UIC)低于 100μg/L 的人群的碘状态,以提示碘缺乏。法罗群岛的人群碘摄入量没有数据。本研究旨在提供法罗群岛一般成年人群代表性样本中碘营养状况的数据。我们于 2011-2012 年进行了一项基于人群的横断面调查,使用 ceri/arsen 法在碱性灰化后测量了 491 名参与者(294/197 名男性/女性)尿液中的碘。参与者包括四个成年十年中的每个十年约 100 名受试者,包括来自首都和村庄的参与者。UIC 在推荐范围内较低,为 101μg/l(范围为 21-1870μg/l)。没有样本在严重碘缺乏的范围内,但一半的样本在仅足够或轻度碘摄入不足的范围内,女性的 UIC 明显低于男性(86 对 115μg/l;P<0.001)。鱼和鲸鱼肉的摄入量影响 UIC。总之,近一半的人口的碘排泄量处于边缘或轻度碘缺乏的范围内。法罗群岛女性的最低碘营养水平令人担忧,因为这可能会扩展到怀孕期,对碘营养的需求增加。此外,我们发现,碘摄入量的巨大变化和间歇性过量需要在法罗群岛人群中监测甲状腺功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66a0/8980727/9cbf0c119b82/S0007114521001938_fig1.jpg

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