Sekiguchi Ryo, Urabe Naohisa, Sakamoto Susumu, Sasaki Masakazu, Homma Sakae, Kishi Kazuma
Department of Respiratory Medicine Toho University Omori Medical Center Tokyo Japan.
Department of Clinical Laboratory Toho University Omori Medical Center Tokyo Japan.
Respirol Case Rep. 2021 May 25;9(6):e00783. doi: 10.1002/rcr2.783. eCollection 2021 Jun.
is a black fungus that rarely causes respiratory infection. We report a case of . pneumonia with bronchiectasis that relapsed after 11 months of voriconazole (VRCZ) treatment in a rheumatoid arthritis (RA) patient with bronchiectasis. A 65-year-old woman with RA and abnormal findings on chest radiography was referred for assessment of chronic cough and increased sputum production. She underwent bronchoscopy, and . was identified from bronchoalveolar lavage fluid (BALF). chronic lower respiratory tract infection and pneumonia were diagnosed. Although her condition improved after 11 months of VRCZ treatment, chest computed tomography (CT) images showed worsening at five months after the cessation of VRCZ treatment and . was again detected in BALF. Re-administration of VRCZ for two years improved symptoms and chest CT images, and her condition is currently stable. In patients with bronchiectasis, . pneumonia might require prolonged antifungal treatment.
是一种罕见引起呼吸道感染的黑色真菌。我们报告一例类风湿关节炎（RA）合并支气管扩张患者，在接受伏立康唑（VRCZ）治疗11个月后发生肺炎并支气管扩张复发。一名65岁患有RA且胸部X线检查有异常表现的女性因慢性咳嗽和痰液增多前来评估。她接受了支气管镜检查，并从支气管肺泡灌洗液（BALF）中鉴定出……诊断为慢性下呼吸道感染和肺炎。尽管VRCZ治疗11个月后她的病情有所改善，但胸部计算机断层扫描（CT）图像显示在VRCZ治疗停止5个月后病情恶化，且在BALF中再次检测到……重新给予VRCZ治疗两年后症状和胸部CT图像有所改善，她目前病情稳定。对于支气管扩张患者，……肺炎可能需要长期抗真菌治疗。
