McGlone R, Heyes F, Harris P
General Infirmary, Leeds, England.
Arch Emerg Med. 1988 Jun;5(2):79-85. doi: 10.1136/emj.5.2.79.
In searching for the 'ideal' muscle relaxant for use with intravenous regional anaesthesia, muscle relaxation was assessed with and without the addition of Atracurium to Bier's Block in four volunteers. This was followed by a clinical study of 36 patients with wrist fractures to confirm the drug's safety and examine the possible clinical advantages of using a muscle relaxant. The addition of 2 mg of Atracurium to the Bier's Block improved the ease of reduction (P less than 0.025) and the quality of analgesia (P less than 0.05) (Mann-Whitney U test). The authors conclude that the addition of Atracurium to a Bier's Block is useful in selected patients with a wrist fracture.
在寻找用于静脉区域麻醉的“理想”肌肉松弛剂时,对四名志愿者在 Bier 阻滞中添加阿曲库铵和不添加阿曲库铵的情况下进行了肌肉松弛评估。随后对 36 例腕部骨折患者进行了临床研究,以确认该药物的安全性,并研究使用肌肉松弛剂可能的临床优势。在 Bier 阻滞中添加 2 mg 阿曲库铵可提高复位的 ease(P 小于 0.025)和镇痛质量(P 小于 0.05)(曼-惠特尼 U 检验)。作者得出结论,在 Bier 阻滞中添加阿曲库铵对选定的腕部骨折患者有用。 (注:原文中“ease”此处可能有误,推测可能是“efficacy”即“效果、效力”之意 )