Migliari R, Scarpa R M, Vanni R, Ruggiero V, Usai E
Department of Urology, University of Cagliari, Italy.
Br J Urol. 1988 Jul;62(1):32-5. doi: 10.1111/j.1464-410x.1988.tb04260.x.
A multidisciplinary diagnostic approach to a case of bladder carcinoma in a 19-year-old male smoker is presented. The transitional cell carcinoma was submitted to conventional histological examination, flow cytometry and cytogenetic analysis. Serum and urine tumour markers were also investigated. The tumour was diploid, with an increased proliferative phase, and a chromosome marker was found. A net decrease in serum and urine ferritin concentrations was noted after transurethral resection of the neoplasm and its low malignancy was confirmed at follow-up.
本文介绍了一名19岁男性吸烟患者膀胱癌病例的多学科诊断方法。将移行细胞癌进行常规组织学检查、流式细胞术和细胞遗传学分析。还对血清和尿液肿瘤标志物进行了研究。肿瘤为二倍体，增殖期增加，并发现一个染色体标志物。经尿道肿瘤切除术后血清和尿液铁蛋白浓度出现净下降，随访证实其恶性程度较低。
